Out-of-sample fit and posterior predictive plots for the left inferior temporal region.

<p>The local FKPP model was iteratively calibrated to a ADNI cohort with 41 in-sample subjects and 16 test subjects. Three iterations were run where for each iteration an additional scan from the test subjects were included, starting with a single scan. Posterior predictive trajectories for le...

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Bibliographic Details
Main Author:	Pavanjit Chaggar (9515394) (author)
Other Authors:	Jacob W. Vogel (17601848) (author), Alexa Pichet Binette (17282919) (author), Travis B. Thompson (9515391) (author), Olof Strandberg (5612342) (author), Niklas Mattsson-Carlgren (15238039) (author), Linda Karlsson (368463) (author), Erik Stomrud (371678) (author), Saad Jbabdi (117812) (author), Stefano Magon (513040) (author), Gregory Klein (4673425) (author), Oskar Hansson (233854) (author), Alain Goriely (1669849) (author)
Published:	2025
Subjects:	Genetics Molecular Biology Neuroscience Biotechnology Science Policy Mental Health Infectious Diseases Biological Sciences not elsewhere classified Information Systems not elsewhere classified xlink "> aggregation two independent cohorts predict accurately subject new clinical tool alzheimer &# 8217 tau pet data pathological tau seeds hyperphosphorylated tau protein rich spatiotemporal pattern local tau production disease exhibiting transport pathologic tau spatiotemporal process local production transport dynamics sequentially progressing regional level potentially providing early stage disease timeline central driver brain regions accumulation exhibits
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Out-of-sample fit and posterior predictive plots for the left inferior temporal region.

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