Anti-PD-L1 Antibody Fragment Linked to Tumor-Targeting Lipid Nanoparticle Can Eliminate Cancer and Its Metastasis via Photoimmunotherapy

Anti-PD-L1 Antibody Fragment Linked to Tumor-Targeting Lipid Nanoparticle Can Eliminate Cancer and Its Metastasis via Photoimmunotherapy

Effective cancer therapy aims to treat primary tumors and metastatic and recurrent cancer. Immune checkpoint blockade-mediated immunotherapy has shown promising effects against tumors; however, its efficacy in metastatic or recurrent cancer is limited. Here, based on the advantages of nanomedicine,...

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Bibliographic Details
Main Author: Hae-Bin Park (7248422) (author)
Other Authors: Eun-Koung An (11383579) (author), So-Jung Kim (1644736) (author), Dayoung Ryu (15800385) (author), Wei Zhang (405) (author), Chan-Gi Pack (4046764) (author), Hyuncheol Kim (229339) (author), Minseok Kwak (612977) (author), Wonpil Im (79057) (author), Ja-Hyoung Ryu (1532641) (author), Peter C. W. Lee (6855368) (author), Jun-O Jin (473261) (author)
Published: 2024
Subjects:
Medicine
Cell Biology
Pharmacology
Biotechnology
Immunology
Cancer
Plant Biology
Chemical Sciences not elsewhere classified
shown promising effects
mice previously cured
immune checkpoint blockade
intravenously injected pilnps
targeting lipid nanoparticle
performing ptt using
4t1 breast tumor
treat primary tumors
metastatic recurrent cancer
treat primary
recurrent cancer
termed pilnps
targeting tumors
lipid nanoparticles
4t1 tumor
eliminate cancer
target tumors
prevent metastasis
photothermal therapy
l1 antibody
infrared laser
indocyanine green
completely prevented
bearing balb
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