Effects of PAI-1 deficiency on trabecular bone with the administration of adenine diets.

(A-E) Trabecular bone mineral density (BMD) (A), the bone volume fraction (BV/TV) (B), trabecular number (Tb.N) (C), trabecular thickness (Tb.Th) (D), and trabecular separation (Tb.Sp) (E) in PAI-1+/+ and PAI-1-/- mice of both sexes analyzed usi...

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Main Author:	Yuya Mizukami (6558758) (author)
Other Authors:	Naoyuki Kawao (181472) (author), Takashi Ohira (153053) (author), Kiyotaka Okada (226871) (author), Hisatoshi Yamao (19832233) (author), Osamu Matsuo (181485) (author), Hiroshi Kaji (540508) (author)
Published:	2024
Subjects:	Biochemistry Medicine Cell Biology Genetics Physiology Science Policy Hematology tibialis anterior muscles sup >-/-</ sup sup >+/+</ sup quantitative computed tomography present study investigated femoral microstructural parameters chronic kidney disease div >< p sarcopenia remain unknown plasminogen activator inhibitor often involves ckd muscle weight measurement grip strength test mice </ p 1 deficiency also muscle wasting induced induced renal dysfunction induced female mice induced male mice renal dysfunction muscle wasting grip strength female mice induced mice muscle mass body weight 1 deficiency induced sarcopenia induced decreases deficient mice trabecular bone tissue weights ten weeks sarcopenia caused partly related lower limbs inflammatory conditions food intake ckd state bone metabolism bone loss bone disorders bone disorder 1 may
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Effects of PAI-1 deficiency on trabecular bone with the administration of adenine diets.

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