Comparison of PD-1, PD-L1, and PD-L2 mRNA gene expression level (fold change) in endometrium tissue from control group and EC patients.

Comparison of PD-1, PD-L1, and PD-L2 mRNA gene expression level (fold change) in endometrium tissue from control group and EC patients.

<p>The levels of mRNA expression have been normalized with housekeeping gene (GAPDH and ACTB). Mann–Whitney U test was used to compare the expression. * indicates <i>p</i> < 0.050. ns indicates not significantly different.</p>

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Bibliographic Details
Main Author:	Mohd Nazzary Mamat @ Yusof (20833546) (author)
Other Authors:	Kah Teik Chew (12003690) (author), Nirmala Chandralega Kampan (20833549) (author), Abdul Muzhill Hannaan Abdul Hafizz (20833552) (author), Mohamad Nasir Shafiee (20833555) (author)
Published:	2025
Subjects:	Biophysics Biochemistry Cell Biology Molecular Biology Immunology Biological Sciences not elsewhere classified Mathematical Sciences not elsewhere classified potential predictive biomarkers soluble protein levels soluble protein level vascular space invasion mrna gene expression type ii ec negative immunoregulatory molecules l2 may serve l1 protein level clinical profiles except higher gene expression endometrial cancer patients assist tumour cells gene expression endometrial cancer clinical profiles myometrial invasion substantially higher significantly higher higher grade soluble pd tumour cells tregs ). study investigates significantly elevated results showed infiltrating lymphocytes immunosuppressive regulatory immune system immune response fully elucidated findings suggest ec compared detailed analysis advanced stages advanced stage
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