Thermoneutrality decreased sepsis survival.

Thermoneutrality decreased sepsis survival.

<p>Mice were acclimated at either 22°C or 30°C for seven days and returned to their respective housing temperatures for observation up to 7 days after CLP. n = 10 mice/group, * = p < 0.05.</p>

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Bibliographic Details
Main Author:	Goldia Chan (21453340) (author)
Other Authors:	Christopher Fry (3476120) (author), Jean Nemzek (780461) (author)
Published:	2025
Subjects:	Medicine Cell Biology Physiology Evolutionary Biology Ecology Immunology Inorganic Chemistry Infectious Diseases Environmental Sciences not elsewhere classified Biological Sciences not elsewhere classified Chemical Sciences not elsewhere classified less robust influx increased systemic il 62 x 10 30 ° c 22 ° c 62 ± 0 55 ± 0 52 ± 0 38 ± 0 10 ± 0 9 ± 1 68 ± 1 20 ± 2 8 ± 3 68 vs 2 7 ° c 4 ± 1 murine sepsis model div >< p 7 ± 4 80 ± 0 temperature acclimation followed 4 </ sup 3 vs 1 3 </ sup standard housing temperatures murine model 20 vs vitro </ ambient temperature 57 vs 3 x10 07 vs temperatures within standard temperatures stimulated splenocytes significantly lower peritoneal macrophages one week lower survival important variable experimentation phases day mortality acclimation period 76 x10 6 levels 54 x10 46 x10 24 hours 004 ).
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