Biochemical/enzymatic assays, computational stability and dimerization affinity data.

<p>(<b>A</b>) Left: dose response experiment of WT, L57F, L167F/P168S and L167F/P168S/L57F with nirmatrelvir (± SD; n = 2 technical replicates). Right: dose response experiment of WT, L57F, L167F/P168S and L167F/P168S/L57F with ensitrelvir (± SD; n = 2 technical replicates). (<b...

وصف كامل

محفوظ في:

التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Francesco Costacurta (19648605) (author)
مؤلفون آخرون:	Andrea Dodaro (17379409) (author), David Bante (13764181) (author), Helge Schöppe (19648608) (author), Ju-Yi Peng (8056349) (author), Bernhard Sprenger (10130179) (author), Xi He (208289) (author), Seyed Arad Moghadasi (19648611) (author), Lisa Maria Egger (19648614) (author), Jakob Fleischmann (19648617) (author), Matteo Pavan (8622047) (author), Davide Bassani (11170376) (author), Silvia Menin (13010133) (author), Stefanie Rauch (4397815) (author), Laura Krismer (19648620) (author), Anna Sauerwein (19648623) (author), Anne Heberle (19648626) (author), Toni Rabensteiner (19648629) (author), Joses Ho (214863) (author), Reuben S. Harris (22319) (author), Eduard Stefan (18222921) (author), Rainer Schneider (87432) (author), Theresia Dunzendorfer-Matt (19648632) (author), Andreas Naschberger (19648635) (author), Dai Wang (73589) (author), Teresa Kaserer (2542216) (author), Stefano Moro (721559) (author), Dorothee von Laer (307452) (author), Emmanuel Heilmann (11565521) (author)
منشور في:	2024
الموضوعات:	Biophysics Medicine Cell Biology Genetics Molecular Biology Pharmacology Evolutionary Biology Cancer Hematology Infectious Diseases Plant Biology Virology Biological Sciences not elsewhere classified Mathematical Sciences not elsewhere classified Chemical Sciences not elsewhere classified Information Systems not elsewhere classified yet suboptimal concentrations div >< p currently available treatments putative molecular mechanism 2 replicon assays 2 main protease pro </ sup resistant mutants selected silico </ molecular modelling 2 continues variants resistant using wuhan study aimed safely generate resistance phenotype previously developed large set future generation frequently present confer resistance comprehensive study clinical use
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!

Biochemical/enzymatic assays, computational stability and dimerization affinity data.

مواد مشابهة