Background heterogeneity and sequencing depth improve WheresWalker SNPindex.

Background heterogeneity and sequencing depth improve WheresWalker SNPindex.

<p>A-C) regional SNP index profile for datasets generated in an AB or WIK background for <i>arches</i> (A), <i>olympic</i> (B), and <i>teton</i> (C) mutants. D) Het<sup>wt</sup> distribution for <i>arches</i> AB 4x5 and WIK 4x5 datase...

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محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: McKenna Feltes (11242085) (author)
مؤلفون آخرون: Aleksey V. Zimin (8363328) (author), Sofia Angel (21714119) (author), Nainika Pansari (21714122) (author), Monica R. Hensley (3133671) (author), Jennifer L. Anderson (15991713) (author), Meng-Chieh Shen (4608190) (author), Mackenzie Klemek (21714125) (author), Yi Shen (152956) (author), Vighnesh S. Ginde (21714128) (author), Hannah Kozan (21714131) (author), Nhan V. Le (21714134) (author), Vivian P. Truong (21714137) (author), Meredith H. Wilson (6816489) (author), Steven L. Salzberg (8363331) (author), Steven A. Farber (9217109) (author)
منشور في: 2025
الموضوعات:
Medicine
Microbiology
Genetics
Neuroscience
Evolutionary Biology
Infectious Diseases
Virology
Environmental Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Mathematical Sciences not elsewhere classified
supports positional cloning
method using mutants
forward genetic screening
allelic frequency calculations
whereswalker correctly mapped
sequencing approach based
previously unappreciated apob
previously published mutation
div >< p
sequencing algorithm
powerful approach
describe whereswalker
slc3a2a </
potential candidates
mttp </
modifying locus
mia2 </
lipoprotein metabolism
key step
gene causing
drastically reduces
assign functions
1 </
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