Age-associated metabolic profiles of <i>dInr</i><sup><i>E19</i></sup>/<i>dInr</i><sup><i>74</i></sup> and <i>dInr</i><sup>353</sup>/<i>dInr</i><sup>wt</sup>.
<p><b>(A)</b> Heatmap of age-associated metabolites among wildtype (<i>dInr</i><sup>wt/wt</sup>), <i>dInr</i><sup><i>E19</i></sup><i>/dInr</i><sup><i>74</i></sup>, or <i>dInr</i...
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2025
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| Summary: | <p><b>(A)</b> Heatmap of age-associated metabolites among wildtype (<i>dInr</i><sup>wt/wt</sup>), <i>dInr</i><sup><i>E19</i></sup><i>/dInr</i><sup><i>74</i></sup>, or <i>dInr</i><sup>353</sup>/<i>dInr</i><sup>wt</sup>. <b>(B)</b> Methionine metabolism network where significant age-associated changes at day 30 are indicated for each genotype. <b>(C-J)</b> The level of methionine metabolism at day 30 relative to the level within each genotype at day 15 (all values normalized to the mean at day 15): (<b>C</b>) methionine, (<b>D</b>) sarcosine, (<b>E</b>) cystathionine, <b>(F)</b> SAM, (<b>G</b>) methionine sulfoxide, (<b>H</b>) cysteine, (<b>I</b>) taurine, and (<b>J</b>) hypotaurine.</p> |
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