Within host viral load trajectories.

Within host viral load trajectories.

<p>The within-host viral load dynamics over time for 10, 50, 100, 150, 200 and 250 segregating sites, and varying initial numbers of mutations. The viral load of the equilibrium solution is shown by the black dashed horizontal line. The viral load changes as the virus population evolves over t...

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Bibliographic Details
Main Author: Harriet Longley (22756119) (author)
Other Authors: Christophe Fraser (7754) (author), Chris Wymant (4102264) (author), Katrina Lythgoe (6854978) (author)
Published: 2025
Subjects:
Microbiology
Genetics
Biotechnology
Evolutionary Biology
Ecology
Infectious Diseases
Virology
nested modelling approach
xlink "> hiv
sufficiently small effect
slightly deleterious mutations
determine viral load
viral load
hiv severity
viral loads
viral factors
term trajectory
studied example
small number
slow changes
simulated epidemics
selection balance
rapid within
maximises transmission
links within
intermediate level
hosts using
host evolution
gradually reached
genomic evolution
epidemiological outcomes
broad distributions
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