Within host viral load trajectories.

<p>The within-host viral load dynamics over time for 10, 50, 100, 150, 200 and 250 segregating sites, and varying initial numbers of mutations. The viral load of the equilibrium solution is shown by the black dashed horizontal line. The viral load changes as the virus population evolves over t...

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Bibliographic Details
Main Author:	Harriet Longley (22756119) (author)
Other Authors:	Christophe Fraser (7754) (author), Chris Wymant (4102264) (author), Katrina Lythgoe (6854978) (author)
Published:	2025
Subjects:	Microbiology Genetics Biotechnology Evolutionary Biology Ecology Infectious Diseases Virology nested modelling approach xlink "> hiv sufficiently small effect slightly deleterious mutations determine viral load viral load hiv severity viral loads viral factors term trajectory studied example small number slow changes simulated epidemics selection balance rapid within maximises transmission links within intermediate level hosts using host evolution gradually reached genomic evolution epidemiological outcomes broad distributions
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Within host viral load trajectories.

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