Altered mitochondrial DNA methylation in blood in individuals with mild cognitive impairment

Altered mitochondrial DNA methylation in blood in individuals with mild cognitive impairment

<p>Previous studies reported that altered mitochondrial methylation in Alzheimer’s disease (AD), however, whether epigenetic modifications in mitochondrial genomes contribute to preclinical AD remains unclear. This study aimed to investigate mitochondrial methylation changes in individuals wit...

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Autore principale: Wuzi Tu (22109088) (author)
Altri autori: Ying Jin (107917) (author), Xiaohong Zhang (32960) (author), Xiaofei Ye (510484) (author), Li Hua (1723489) (author), Nannan Feng (9244363) (author)
Pubblicazione: 2025
Soggetti:
Biochemistry
Genetics
Neuroscience
Sociology
Cancer
Mental Health
Chemical Sciences not elsewhere classified
Whole-genome
mitochondrial methylation
bisulfite amplicon sequencing
epigenetic biomarkers
mild cognitive impairment
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