Spearman correlation coefficient (r<sub>s</sub>) between echocardiographic measurements (i.e., left atrial:aortic root diameter; LA:Ao), markers of loss of GI barrier function (i.e., lipopolysaccharide; LPS), and cardiac (i.e., troponin) and systemic (i.e., cytokines) inflammation in 36 dogs with untreated myxomatous mitral valve disease (MMVD).
<p>Spearman correlation coefficient (r<sub>s</sub>) between echocardiographic measurements (i.e., left atrial:aortic root diameter; LA:Ao), markers of loss of GI barrier function (i.e., lipopolysaccharide; LPS), and cardiac (i.e., troponin) and systemic (i.e., cytokines) inflammati...
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2025
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| _version_ | 1849927643203371008 |
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| author | Maria C. Jugan (18928389) |
| author2 | Gabrielle A. Rands (22676472) Joerg M. Steiner (6887384) Natalia Cernicchiaro (783181) Matthew C. Tanner (22676475) Lillian M. Novotny (22676478) |
| author2_role | author author author author author |
| author_facet | Maria C. Jugan (18928389) Gabrielle A. Rands (22676472) Joerg M. Steiner (6887384) Natalia Cernicchiaro (783181) Matthew C. Tanner (22676475) Lillian M. Novotny (22676478) |
| author_role | author |
| dc.creator.none.fl_str_mv | Maria C. Jugan (18928389) Gabrielle A. Rands (22676472) Joerg M. Steiner (6887384) Natalia Cernicchiaro (783181) Matthew C. Tanner (22676475) Lillian M. Novotny (22676478) |
| dc.date.none.fl_str_mv | 2025-11-24T18:26:09Z |
| dc.identifier.none.fl_str_mv | 10.1371/journal.pone.0337580.t004 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/dataset/Spearman_correlation_coefficient_r_sub_s_sub_between_echocardiographic_measurements_i_e_left_atrial_aortic_root_diameter_LA_Ao_markers_of_loss_of_GI_barrier_function_i_e_lipopolysaccharide_LPS_and_cardiac_i_e_troponin_and_systemic_i_e_cytok/30696807 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Medicine Microbiology Cell Biology Physiology Biotechnology Ecology Immunology Cancer Science Policy Biological Sciences not elsewhere classified Chemical Sciences not elsewhere classified muscle condition score linear regression models fisher exact test evaluate possible associations body condition score gastrointestinal barrier function inflammatory biomarkers based stage c disease gastrointestinal clinical signs lps ), interleukins including 25 dogs e ., il div >< p stage b2 disease gastrointestinal bacterial translocation group 2 ), mmvd stage severity gastrointestinal signs bacterial translocation b2 disease gastrointestinal microbiome inflammatory markers disease progresses cardiovascular disease group 2 group 1 xlink "> untreated mmvd twenty percent therapeutic targets study indicates study aimed spearman ’ six client serum lps serum lipopolysaccharide serum il potential relationship positively correlated owned dogs mmvd severity mmvd ). maybe even groups 1 findings warrant fecal scores enrolled prospectively echocardiographic diagnosis compare proportions compare lps |
| dc.title.none.fl_str_mv | Spearman correlation coefficient (r<sub>s</sub>) between echocardiographic measurements (i.e., left atrial:aortic root diameter; LA:Ao), markers of loss of GI barrier function (i.e., lipopolysaccharide; LPS), and cardiac (i.e., troponin) and systemic (i.e., cytokines) inflammation in 36 dogs with untreated myxomatous mitral valve disease (MMVD). |
| dc.type.none.fl_str_mv | Dataset info:eu-repo/semantics/publishedVersion dataset |
| description | <p>Spearman correlation coefficient (r<sub>s</sub>) between echocardiographic measurements (i.e., left atrial:aortic root diameter; LA:Ao), markers of loss of GI barrier function (i.e., lipopolysaccharide; LPS), and cardiac (i.e., troponin) and systemic (i.e., cytokines) inflammation in 36 dogs with untreated myxomatous mitral valve disease (MMVD).</p> |
| eu_rights_str_mv | openAccess |
| id | Manara_2c4b16b40c3b8f0a60b0cd707d78e58d |
| identifier_str_mv | 10.1371/journal.pone.0337580.t004 |
| network_acronym_str | Manara |
| network_name_str | ManaraRepo |
| oai_identifier_str | oai:figshare.com:article/30696807 |
| publishDate | 2025 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Spearman correlation coefficient (r<sub>s</sub>) between echocardiographic measurements (i.e., left atrial:aortic root diameter; LA:Ao), markers of loss of GI barrier function (i.e., lipopolysaccharide; LPS), and cardiac (i.e., troponin) and systemic (i.e., cytokines) inflammation in 36 dogs with untreated myxomatous mitral valve disease (MMVD).Maria C. Jugan (18928389)Gabrielle A. Rands (22676472)Joerg M. Steiner (6887384)Natalia Cernicchiaro (783181)Matthew C. Tanner (22676475)Lillian M. Novotny (22676478)MedicineMicrobiologyCell BiologyPhysiologyBiotechnologyEcologyImmunologyCancerScience PolicyBiological Sciences not elsewhere classifiedChemical Sciences not elsewhere classifiedmuscle condition scorelinear regression modelsfisher exact testevaluate possible associationsbody condition scoregastrointestinal barrier functioninflammatory biomarkers basedstage c diseasegastrointestinal clinical signslps ), interleukinsincluding 25 dogse ., ildiv >< pstage b2 diseasegastrointestinal bacterial translocationgroup 2 ),mmvd stage severitygastrointestinal signsbacterial translocationb2 diseasegastrointestinal microbiomeinflammatory markersdisease progressescardiovascular diseasegroup 2group 1xlink ">untreated mmvdtwenty percenttherapeutic targetsstudy indicatesstudy aimedspearman ’six clientserum lpsserum lipopolysaccharideserum ilpotential relationshippositively correlatedowned dogsmmvd severitymmvd ).maybe evengroups 1findings warrantfecal scoresenrolled prospectivelyechocardiographic diagnosiscompare proportionscompare lps<p>Spearman correlation coefficient (r<sub>s</sub>) between echocardiographic measurements (i.e., left atrial:aortic root diameter; LA:Ao), markers of loss of GI barrier function (i.e., lipopolysaccharide; LPS), and cardiac (i.e., troponin) and systemic (i.e., cytokines) inflammation in 36 dogs with untreated myxomatous mitral valve disease (MMVD).</p>2025-11-24T18:26:09ZDatasetinfo:eu-repo/semantics/publishedVersiondataset10.1371/journal.pone.0337580.t004https://figshare.com/articles/dataset/Spearman_correlation_coefficient_r_sub_s_sub_between_echocardiographic_measurements_i_e_left_atrial_aortic_root_diameter_LA_Ao_markers_of_loss_of_GI_barrier_function_i_e_lipopolysaccharide_LPS_and_cardiac_i_e_troponin_and_systemic_i_e_cytok/30696807CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/306968072025-11-24T18:26:09Z |
| spellingShingle | Spearman correlation coefficient (r<sub>s</sub>) between echocardiographic measurements (i.e., left atrial:aortic root diameter; LA:Ao), markers of loss of GI barrier function (i.e., lipopolysaccharide; LPS), and cardiac (i.e., troponin) and systemic (i.e., cytokines) inflammation in 36 dogs with untreated myxomatous mitral valve disease (MMVD). Maria C. Jugan (18928389) Medicine Microbiology Cell Biology Physiology Biotechnology Ecology Immunology Cancer Science Policy Biological Sciences not elsewhere classified Chemical Sciences not elsewhere classified muscle condition score linear regression models fisher exact test evaluate possible associations body condition score gastrointestinal barrier function inflammatory biomarkers based stage c disease gastrointestinal clinical signs lps ), interleukins including 25 dogs e ., il div >< p stage b2 disease gastrointestinal bacterial translocation group 2 ), mmvd stage severity gastrointestinal signs bacterial translocation b2 disease gastrointestinal microbiome inflammatory markers disease progresses cardiovascular disease group 2 group 1 xlink "> untreated mmvd twenty percent therapeutic targets study indicates study aimed spearman ’ six client serum lps serum lipopolysaccharide serum il potential relationship positively correlated owned dogs mmvd severity mmvd ). maybe even groups 1 findings warrant fecal scores enrolled prospectively echocardiographic diagnosis compare proportions compare lps |
| status_str | publishedVersion |
| title | Spearman correlation coefficient (r<sub>s</sub>) between echocardiographic measurements (i.e., left atrial:aortic root diameter; LA:Ao), markers of loss of GI barrier function (i.e., lipopolysaccharide; LPS), and cardiac (i.e., troponin) and systemic (i.e., cytokines) inflammation in 36 dogs with untreated myxomatous mitral valve disease (MMVD). |
| title_full | Spearman correlation coefficient (r<sub>s</sub>) between echocardiographic measurements (i.e., left atrial:aortic root diameter; LA:Ao), markers of loss of GI barrier function (i.e., lipopolysaccharide; LPS), and cardiac (i.e., troponin) and systemic (i.e., cytokines) inflammation in 36 dogs with untreated myxomatous mitral valve disease (MMVD). |
| title_fullStr | Spearman correlation coefficient (r<sub>s</sub>) between echocardiographic measurements (i.e., left atrial:aortic root diameter; LA:Ao), markers of loss of GI barrier function (i.e., lipopolysaccharide; LPS), and cardiac (i.e., troponin) and systemic (i.e., cytokines) inflammation in 36 dogs with untreated myxomatous mitral valve disease (MMVD). |
| title_full_unstemmed | Spearman correlation coefficient (r<sub>s</sub>) between echocardiographic measurements (i.e., left atrial:aortic root diameter; LA:Ao), markers of loss of GI barrier function (i.e., lipopolysaccharide; LPS), and cardiac (i.e., troponin) and systemic (i.e., cytokines) inflammation in 36 dogs with untreated myxomatous mitral valve disease (MMVD). |
| title_short | Spearman correlation coefficient (r<sub>s</sub>) between echocardiographic measurements (i.e., left atrial:aortic root diameter; LA:Ao), markers of loss of GI barrier function (i.e., lipopolysaccharide; LPS), and cardiac (i.e., troponin) and systemic (i.e., cytokines) inflammation in 36 dogs with untreated myxomatous mitral valve disease (MMVD). |
| title_sort | Spearman correlation coefficient (r<sub>s</sub>) between echocardiographic measurements (i.e., left atrial:aortic root diameter; LA:Ao), markers of loss of GI barrier function (i.e., lipopolysaccharide; LPS), and cardiac (i.e., troponin) and systemic (i.e., cytokines) inflammation in 36 dogs with untreated myxomatous mitral valve disease (MMVD). |
| topic | Medicine Microbiology Cell Biology Physiology Biotechnology Ecology Immunology Cancer Science Policy Biological Sciences not elsewhere classified Chemical Sciences not elsewhere classified muscle condition score linear regression models fisher exact test evaluate possible associations body condition score gastrointestinal barrier function inflammatory biomarkers based stage c disease gastrointestinal clinical signs lps ), interleukins including 25 dogs e ., il div >< p stage b2 disease gastrointestinal bacterial translocation group 2 ), mmvd stage severity gastrointestinal signs bacterial translocation b2 disease gastrointestinal microbiome inflammatory markers disease progresses cardiovascular disease group 2 group 1 xlink "> untreated mmvd twenty percent therapeutic targets study indicates study aimed spearman ’ six client serum lps serum lipopolysaccharide serum il potential relationship positively correlated owned dogs mmvd severity mmvd ). maybe even groups 1 findings warrant fecal scores enrolled prospectively echocardiographic diagnosis compare proportions compare lps |