Synthesis of Hexahydro‑1<i>H</i>‑isoindole Derivatives from Arylacyl Bromides via Homoallenic Bromohydrins

Synthesis of Hexahydro‑1<i>H</i>‑isoindole Derivatives from Arylacyl Bromides via Homoallenic Bromohydrins

A procedure has been developed for the concise synthesis of hexahydro-1<i>H</i>-isoindole derivatives starting from phenacyl bromides. The approach employs a sequence involving an initial indium-mediated allenylation reaction of an arylacyl bromide with propargyl bromide. This process is...

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Bibliographic Details
Main Author: Mei-Huey Lin (1651900) (author)
Other Authors: Yi-Syuan Li (1651906) (author), Chung-Kai Kuo (1651897) (author), Chung-Hao Chen (1651912) (author), Yen-Chih Huang (1651909) (author), Kung-Yu Liang (1651915) (author), Yu-Chun Chen (162910) (author), Chang-Hsien Tsai (1651894) (author), Tsung-Hsun Chuang (1651903) (author)
Published: 2015
Subjects:
Biochemistry
Genetics
Molecular Biology
Biotechnology
Developmental Biology
Infectious Diseases
Virology
Computational Biology
Biological Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
hexahydro
Arylacyl Bromides
propargyl bromide
phenacyl bromides
homoallenic bromohydrin
Homoallenic BromohydrinsA procedure
arylacyl bromide
SN
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