Distribution, expression and prognostic characteristics of different types of immune cells in different immune subtypes of glioma.

<p>(A, B) The heat map showed the results of unsupervised cluster analysis of different immune cells in the CGGA and TCGA databases. (C, D) The Kaplan-Meier survival curve and Scatter plot showed the prognostic characteristics and expression of different immune cells in each immune subtype.<...

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Bibliographic Details
Main Author:	Feng Yuan (551145) (author)
Other Authors:	Yingshuai Wang (4601143) (author), Lei Yuan (713591) (author), Lei Ye (104076) (author), Yangchun Hu (9227351) (author), Hongwei Cheng (327999) (author), Yan Li (23143) (author)
Published:	2024
Subjects:	Medicine Cell Biology Evolutionary Biology Immunology Developmental Biology Cancer Biological Sciences not elsewhere classified tnf signaling pathway mitotic nuclear division important factors hindering central nervous system represent different tmes immunosuppressive tumor microenvironment immune cell distribution enrichment analysis revealed xlink "> firstly myeloid dendritic cells immune tolerance subtype highly reliable model four different subtypes different immune subtypes based new classification stemness maintenance phenotypes mainly closely related xlink "> glioma gliomas </ p xlink "> stemness maintenance immune microenvironment classification model closely related four subtypes different stages mainly enriched immune therapy immune infiltration highest enrichment neuronal phenotypes mesenchymal subtype mesenchymal phenotypes immunogenic subtype highly heterogeneous highly correlated closely associated use david tumorigenic cytokines tcga database study aims strongly associated providing guidance nk cells neuronal phenotype monocytic lineage mesenchymal phenotype machine learning lowest proportion limited efficacy leukocyte activation idh mutation highest proportion highest expressed defined gliomas cytotoxic lymphocytes comprehensively analyzed clinical features cgga database 702 gliomas 693 gliomas 19q13 co
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Distribution, expression and prognostic characteristics of different types of immune cells in different immune subtypes of glioma.

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