Comparison of structural motifs for G protein activation between GPR1 (dark blue) and CMKLR1 (cyan).

Comparison of structural motifs for G protein activation between GPR1 (dark blue) and CMKLR1 (cyan).

<p>The residues responsible for G protein activation are highlighted in sticks. The G protein in the GPR1-Gi structure is shown in magenta, and the G protein in the CMKLR1-Gi structure is shown in light pink.</p> <p>(TIFF)</p>

Saved in:

Bibliographic Details
Main Author:	Aijun Liu (5579711) (author)
Other Authors:	Yezhou Liu (6718037) (author), Geng Chen (194556) (author), Wenping Lyu (3773128) (author), Fang Ye (112854) (author), Junlin Wang (4029803) (author), Qiwen Liao (3905665) (author), Lizhe Zhu (383604) (author), Yang Du (506908) (author), Richard D. Ye (2353900) (author)
Published:	2024
Subjects:	Biophysics Biochemistry Cell Biology Molecular Biology Evolutionary Biology Inorganic Chemistry Infectious Diseases Chemical Sciences not elsewhere classified Physical Sciences not elsewhere classified molecular dynamics simulations site &# 8221 lid &# 8221 coupled receptor 1 xlink "> chemerin like receptor 1 structural model explains length chemerin uses 3 g protein coupled gpr1 bound tm binding pocket c chemokine receptor length chemerin g protein binding pocket coupled receptors &# 8220 like 2 chemerin binds yfpgqfafs ). terminal nonapeptide terminal core resolution cryo present high including chemokine gpr1 signaling gpr1 ), functional assays energetically expensive em structures combining results chemotactic activity ccrl2 ). activating peptide
Tags:	Add Tag No Tags, Be the first to tag this record!

Cannot write session to /tmp/vufind_sessions/sess_rm37svlnf2qgdcn0j0e0u1fjdu