The effect of membrane curvature on the time delay.

<p>(A-B) The dynamics of Ca<sup>2+</sup> and cAMP for inward membrane (A) and outward membrane (B). Only two locations are considered: on the center of AKAP/AC nanodomains (i), and at the edge of the membrane (ii). (C) The in-phase and inversely out-of-phase cAMP behavior in (A-B)....

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Bibliographic Details
Main Author:	Lingxia Qiao (19996756) (author)
Other Authors:	Michael Getz (17692612) (author), Ben Gross (2993145) (author), Brian Tenner (138904) (author), Jin Zhang (53297) (author), Padmini Rangamani (4740435) (author)
Published:	2024
Subjects:	Biophysics Biochemistry Microbiology Cell Biology Genetics Neuroscience Physiology Immunology Cancer Science Policy Biological Sciences not elsewhere classified previous experimental studies key circuit motif incoherent feedforward loop develop computational models adenylyl cyclase 8 two important predictions many cellular functions arbitrary phase difference div >< p camp peak simultaneously 2 +</ sup ac nanodomain formation phase oscillations associated enzymes associated two nanodomains ac nanodomains volume ratio turing pattern time delay spatiotemporal orchestration spatial compartmentation signaling molecules second messengers nanoscale organization low level governs camp give rise findings unveil ensuring compartmentation compartment size cellular surface camp oscillations
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The effect of membrane curvature on the time delay.

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