Expression of <i>mcp5</i> in the enzootic cycle of <i>B</i>. <i>burgdorferi</i>.

Expression of <i>mcp5</i> in the enzootic cycle of <i>B</i>. <i>burgdorferi</i>.

<p>Relative <i>mcp5</i> expression in various stages in ticks (<b>A</b>) and mice (<b>B</b>) was determined by qRT-PCR analyses and reported as copies of <i>mcp5</i> per 1,000 copies of the <i>flaB</i> transcripts. For gene expression...

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Bibliographic Details
Main Author:	Sajith Raghunandanan (9515281) (author)
Other Authors:	Kai Zhang (102844) (author), Yan Zhang (8098) (author), Raj Priya (20485904) (author), Ching Wooen Sze (4423360) (author), Yongliang Lou (416743) (author), Michael J. Lynch (6294167) (author), Brian R. Crane (281294) (author), Mark H. Kaplan (11797881) (author), Chunhao Li (5949533) (author), X. Frank Yang (9515287) (author)
Published:	2024
Subjects:	Microbiology Genetics Molecular Biology Immunology Cancer Infectious Diseases Environmental Sciences not elsewhere classified severe combined immunodeficiency mutants survived feeding gene encoding one nk cell depletion evading nk cell innate immune responses chemotactic signals sensed mutant enhanced interferon accepting chemotaxis proteins underscoring mcp5 ’ nod scid gamma highlighting mcp5 ’ spirochetes lacking mcp5 scid mice restored borrelia burgdorferi </ nk cells burgdorferi </ borrelia </ spirochete ’ pathogen ’ mcp5 </ immune evasion gamma production environmental signals mcp5 plays borreliella </ b </ work provides well known tick vector rpos pathways remains unclear mutant revealed mammalian infection mammalian hosts mammalian host macrophages revealed lyme disease infectious cycle infection experiments hen mice findings reveal establishing infection establish infections establish infection enzootic cycle distinct stages differentially expressed culture assays causative agent associated immunity arthropod vector
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