Structural Tuning of Partial RXR Agonism and Antagonism

Retinoid X receptors (RXRs) represent a central switch in nuclear receptor signaling and appear to hold therapeutic potential in diverse indications. However, the ability of RXR agonists to activate multiple nuclear receptor heterodimers gives rise to adverse effects, which may be avoided by partial...

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主要作者: Max Lewandowski (17811604) (author)
其他作者: Marie Granger--Rivière (22671749) (author), Domenic Mayer (22671752) (author), Till Kasch (17605823) (author), Felix Nawa (15999053) (author), Markus Egner (17049285) (author), Julian A. Marschner (14277781) (author), Vasily Morozov (4870435) (author), Daniel Merk (1373682) (author)
出版: 2025
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