LASSO regression screening of key targets and their internal validation analysis.

A-B. Lasso regression was used to screen key targets, and 3 of them were identified as key targets of microplastics acting in AR. C. Prognostic heatmap demonstrating the expression profile data of 3 key targets in AR. The upper part of it represents the...

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التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Yaojun Wang (309584) (author)
مؤلفون آخرون:	Dandan Xu (149923) (author)
منشور في:	2025
الموضوعات:	Biochemistry Cell Biology Genetics Molecular Biology Neuroscience Cancer Infectious Diseases Chemical Sciences not elsewhere classified xlink "> microplastics pvc ], polystyrene promising therapeutic candidate pe ], polypropylene global health risks four typical mps 82 &# 8211 ppi network analysis respiratory toxicity pathways potential therapeutics predicted mapk9 (&# 8722 critical molecular mediators mol ), suggesting ocular toxicity network toxicology molecular docking inflammatory pathways degs ), core mediators significantly downregulated ps ]) modulating target mitochondrial autophagy microplastic exposure mapk9 serving lasso regression increasingly associated high affinity gse43523 dataset functional enrichment ctd database autodock vina assessed interactions allergic rhinitis 93 ). 8 kcal
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LASSO regression screening of key targets and their internal validation analysis.

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