Image 1_H3K27me3 and HOXA9 expression predict prognosis in pediatric acute myeloid leukemia: an epigenetic-transcriptional correlation study.jpeg

Image 1_H3K27me3 and HOXA9 expression predict prognosis in pediatric acute myeloid leukemia: an epigenetic-transcriptional correlation study.jpeg

Background<p>Epigenetic dysregulation plays a central role in pediatric acute myeloid leukemia (AML), yet its clinical relevance remains underexplored. This study primarily aimed to elucidate the clinical effect of H3K27me3 and H3K4me3 status on pediatric acute myeloid leukemia. We evaluated t...

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Bibliographic Details
Main Author: Hironori Goto (22307641) (author)
Other Authors: Souichi Suenobu (20702643) (author), Yuhki Koga (4530433) (author), Shunsuke Yamamoto (1358631) (author), Kentaro Nakashima (5581277) (author), Utako Oba (8371506) (author), Daiichiro Hasegawa (789404) (author), Ikuya Usami (22307644) (author), Ayako Yamamori (19346700) (author), Hiroshi Moritake (466889) (author), Sumihito Nobusawa (306111) (author), Keisuke Okuno (3746632) (author), Koji Kawaguchi (4719783) (author), Miyako Kanno (22307647) (author), Hisashi Ishida (593816) (author), Yuko Cho (1816657) (author), Haruto Nishida (13920772) (author), Daisuke Tomizawa (14933726) (author), Kenji Ihara (790988) (author), Shouichi Ohga (200079) (author)
Published: 2025
Subjects:
Hematology
H3K27me3
pediatric
AML
HOXA9
H3K4Me3
HOXA cluster genes
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