Data Sheet 1_GSTP1 improves CAR-T cell proliferation and cytotoxicity to combat lymphoma.zip

Data Sheet 1_GSTP1 improves CAR-T cell proliferation and cytotoxicity to combat lymphoma.zip

Introduction<p>The exhaustion of chimeric antigen receptor T cells (CAR-T) hampers the efficacy of CAR-T cell therapy. Persistent antigen stimulation in T cells results in a surge of intracellular reactive oxygen species (ROS). ROS, as mitochondrial metabolites, alter the integrity of the mito...

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Bibliographic Details
Main Author: Guangsong Xu (22315933) (author)
Other Authors: Jiani Wang (3512525) (author), Yuliang Qu (7274339) (author), Jing Ning (1481449) (author), Yanting Zhang (338754) (author), Guangxian Xu (797319) (author), Yunxia Shi (22315936) (author), Ying Li (38224) (author), Le Guo (320752) (author), Xuebo Han (22315939) (author), Hongxia Wang (241142) (author)
Published: 2025
Subjects:
Genetic Immunology
CAR-T cell exhaustion
BLIMP1
GSTP1
oxidative stress
reactive oxygen species
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