Changes in neural selectivity caused by PV cell activation reflect behavioral performance in easy but not difficult discriminations.

<p><b>A)</b> Optogenetic stimulation timings for entire and early window conditions aligned to stimulus onset (STIM ON) or offset (STIM OFF) (top), schematic of optogenetic method combined with 2-photon imaging (middle), schematic of laser activating only ChrimsonR-expressing PV ce...

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Autor Principal:	Lilia Kukovska (22683586) (author)
Outros autores:	Katharina A. Wilmes (22683589) (author), Natsumi Y. Homma (22683592) (author), Claudia Clopath (324706) (author), Jasper Poort (22683595) (author)
Publicado:	2025
Subjects:	Biochemistry Neuroscience Developmental Biology Science Policy Mental Health Biological Sciences not elsewhere classified xlink "> inhibition three major factors strong competitive interactions photon imaging showed balanced cortical activity primary visual cortex sustained v1 activity combined optogenetic activation v1 cells captured moderate pv activation moderate activation visual discriminations expressing cells nonlinear activation dependent activation activation strength task difficulty stimulus onset perceptual discrimination difficult discriminations delineates conditions circuit model behavioral effects
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Changes in neural selectivity caused by PV cell activation reflect behavioral performance in easy but not difficult discriminations.

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