Supplementary Tables S1-S11 from Adult Low-Hypodiploid Acute Lymphoblastic Leukemia Emerges from Preleukemic <i>TP53</i>-Mutant Clonal Hematopoiesis

Supplementary Tables S1-S11 from Adult Low-Hypodiploid Acute Lymphoblastic Leukemia Emerges from Preleukemic <i>TP53</i>-Mutant Clonal Hematopoiesis

<p>Supplementary Table 1. Karyotypes of LH-ALL patients at diagnosis. Supplementary Table 2. Somatic variants detected in LH-ALL patients at diagnosis. Supplementary Table 3. ARCH related variants detected in LH-ALL patients at remission. Supplementary Table 4. Minimal residual disease values...

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Autor principal: Rathana Kim (15135915) (author)
Otros Autores: Hugo Bergugnat (15135918) (author), Lise Larcher (15135921) (author), Matthieu Duchmann (15049433) (author), Marie Passet (15135924) (author), Stéphanie Gachet (15118876) (author), Wendy Cuccuini (15135927) (author), Marina Lafage-Pochitaloff (15135930) (author), Cédric Pastoret (15135933) (author), Nathalie Grardel (15135936) (author), Vahid Asnafi (15135939) (author), Beat W. Schäfer (15135942) (author), Eric Delabesse (15047352) (author), Raphaël Itzykson (15135945) (author), Lionel Adès (15049442) (author), Yosr Hicheri (15135948) (author), Yves Chalandon (15018422) (author), Carlos Graux (15135951) (author), Patrice Chevallier (15135954) (author), Mathilde Hunault (15135957) (author), Thibaut Leguay (15135960) (author), Françoise Huguet (15047328) (author), Véronique Lhéritier (15135963) (author), Hervé Dombret (15049448) (author), Jean Soulier (15135966) (author), Philippe Rousselot (15135969) (author), Nicolas Boissel (15135972) (author), Emmanuelle Clappier (15118873) (author)
Publicado: 2025
Materias:
Cancer
Molecular and Cellular Biology
Therapeutic Research and Development
Methods and Technology
Genome Biology
Hematological Cancers
Leukemias
Single Cell Technologies
Translational Research
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Sumario:<p>Supplementary Table 1. Karyotypes of LH-ALL patients at diagnosis. Supplementary Table 2. Somatic variants detected in LH-ALL patients at diagnosis. Supplementary Table 3. ARCH related variants detected in LH-ALL patients at remission. Supplementary Table 4. Minimal residual disease values of remission samples used for mutation analysis. Supplementary Table 5. Somatic alterations in cell populations from diagnostic samples (BMMC) based on single-cell analyses. Supplementary Table 6. Somatic alterations in FACS-sorted cell populations from diagnostic samples. Supplementary Table 7. Panel of genes for targeted sequencing. Supplementary Table 8. Single cell DNA amplicons for genotyping and LOH analyses. Supplementary Table 9. Single cell DNA amplicons for B-ALL clono-specific IG/TR detection. Supplementary Table 10. ADT-seq panel and spike-in antibodies. Supplementary Table 11. Single cell sequencing metrics.</p>

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