Overall architecture of the SmsC<sub>2</sub>B<sub>2</sub> complex.

Overall architecture of the SmsC<sub>2</sub>B<sub>2</sub> complex.

<p><b>(a)</b> AMP-PNP-loaded SmsC<sub>2</sub>B<sub>2</sub> crystal structure. <b>(b)</b> Close-up on the binding site of the AMP-PNP/Mg<sup>2+</sup> showing residues surrounding the binding site of AMP-PNP. <b>(c)</b> Cryo...

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Main Author: Macha Dussouchaud (21601445) (author)
Other Authors: Markel Martinez-Carranza (21601448) (author), Pierre-Simon Garcia (21601451) (author), Martin Clémancey (347878) (author), Geneviève Blondin (2668756) (author), Jean Michel Betton (21601454) (author), Ahmed Haouz (5624486) (author), Simonetta Gribaldo (3252) (author), Sandrine Ollagnier de Choudens (21601457) (author), Ludovic Sauguet (250490) (author), Ariel Mechaly (12131742) (author), Frédéric Barras (207624) (author)
Published: 2025
Subjects:
Biophysics
Biochemistry
Microbiology
Genetics
Biotechnology
Evolutionary Biology
Cancer
Infectious Diseases
Virology
Chemical Sciences not elsewhere classified
ubiquitous protein co
studied modern iron
present study focuses
mutually exclusive allowing
methanocaldococcus jannaschii </
mechanistic model describing
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contained cys residues
bona fide </
anaerobic prokaryotes prior
structural studies showed
study established sms
sms system rescued
smsc subunit hosts
suf systems grown
cluster binding sites
cluster assembly site
biogenesis system sms
biogenesis system
biogenesis systems
unique structural
cluster assembly
ancestor sms
sulfur cluster
unique mechanism
similar c
regulatory coupling
nif ),
key role
hyperthermophilic archaeon
heterotetratmer wherein
gave rise
functional features
anoxic planet
anoxic conditions
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