Supplementary Figure S6 from Practical Considerations for Using the TITE-BOIN Design to Handle Late-Onset Toxicity or Fast Accrual in Phase I Trials
<p>Comparative performances of TITE-BOIN designs with seven different cutoffs (A, B), denoted as TB(A, B), relative to the standard BOIN design under scenarios 1-6 with target DLT of 0.25. TB(A, B) requires that over A % of the patients treated at the current dose have completed the DLT window...
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2025
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