Renal and urine HexCers and LacCers are increased in OP-treated MRL/lpr mice.

Renal and urine HexCers and LacCers are increased in OP-treated MRL/lpr mice.

<p>Renal GSLs were quantified in renal cortex homogenates from the same mice as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0230499#pone.0230499.g001" target="_blank">Fig 1</a> at the endpoint of the study. (A) Ceramides (Cers). (B)...

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Bibliographic Details
Main Author: Tamara K. Nowling (8595801) (author)
Other Authors: Jessalyn Rodgers (648304) (author), Thirumagal Thiyagarajan (456641) (author), Bethany Wolf (8595804) (author), Evelyn Bruner (8595807) (author), Kamala Sundararaj (8595810) (author), Ivan Molano (8280399) (author), Gary Gilkeson (671653) (author)
Published: 2020
Subjects:
Biochemistry
Medicine
Microbiology
Molecular Biology
Physiology
Ecology
Immunology
Marine Biology
Science Policy
Biological Sciences not elsewhere classified
ganglioside GM 3
MRL
block GSL catabolism
block GSL synthesis
Blocking GSL catabolism
GSL ganglioside pathways
Genz -667161 dose
NEU inhibitor oseltamivir phosphate
lupus nephritis kidneys
GM 3 levels
NEU activity
GM 3
lupus nephritis
lupus mice
GlcCer synthase inhibitor Genz -667161
serum IgG levels
Renal GM 3 levels
Targeting glycosphingolipid metabolism
upregulated GSL synthesis
urine GSL levels
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