Bioengineering Approaches for the 3D Blood–Retinal Barrier: Disease Modeling and Drug Development

The integrity and functionality of the blood–retina barrier (BRB) are essential for maintaining homeostasis of the retina. Disruption of the BRB is a key feature in different stages of retinal diseases including diabetic retinopathy, age-related macular degeneration (AMD), and inherited retinal dise...

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Bibliographic Details
Main Author:	Ruiyi Yan (4594162) (author)
Other Authors:	Yusong Wang (1467721) (author), Yinhan Wang (18289599) (author), Mingchang Pang (22283574) (author), Linfei Wei (22283577) (author), Meijiao Zhu (9758954) (author), Huayu Yang (6328412) (author), Weihong Yu (11091709) (author)
Published:	2025
Subjects:	Medicine Genetics Biotechnology Biological Sciences not elsewhere classified Information Systems not elsewhere classified traditional 2d cultures past three years extracellular matrix scaffolds commonly used techniques related macular degeneration xenogeneic animal models brb holds promise inherited retinal diseases retinal diseases related diseases vitro models brb models vivo brb translational medicine therapeutic strategies simple constructs significant interest retinitis pigmentosa recent advances powerful armament new developments maintaining homeostasis laboratory research key feature investigating mechanistic functional characteristics emphasizing applications drug screening drug development disease modeling disease evolution different stages complex systems biomaterials employed bioengineering approaches amd ),
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Bioengineering Approaches for the 3D Blood–Retinal Barrier: Disease Modeling and Drug Development

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