Representative images of immunohistochemical (IHC) staining and quantification of rhodopsin, opsin, Tuj1, and calbindin in the retina among the three genotypes at 8 and 10 weeks of age.

<p>(A) Rhodopsin IHC images. The brown color in the OS indicates the rhodopsin signals. (B) Quantification of rhodopsin in OS and comparison among the three genotypes at 8 and 10 weeks of age. (C) Opsin IHC images. The brown color in the OS/IS indicates the opsin signals. (D) Quantification of...

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Bibliographic Details
Main Author:	Zhi-Jia Chen (3823780) (author)
Other Authors:	Chun-Yen Wu (11099653) (author), Fang-Yan Hsiao (21370274) (author), Jing-Chun Ma (21370277) (author), Gabriel Lai (11890931) (author), Han-Hsin Chang (55530) (author), David Pei-Cheng Lin (21370280) (author)
Published:	2025
Subjects:	Biophysics Medicine Cell Biology Genetics Neuroscience Developmental Biology Virology Biological Sciences not elsewhere classified retinal layer thickness retinal ganglion cells retinal degeneration characterized related retinal degeneration hyperphosphorylated tau proteins mutant mice retinas glial cell activation klotho protein function null mutation may null mutation leads th </ sup klotho </ null mutation function deprivation cell death mutant retina three genotypes study model study aimed retinopathy caused results revealed functional impairments functional impairment evident damage depth analysis degenerative pathogenesis alzheimer ’ accelerate aging
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Representative images of immunohistochemical (IHC) staining and quantification of rhodopsin, opsin, Tuj1, and calbindin in the retina among the three genotypes at 8 and 10 weeks of age.

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