Figure 5 from The Germline and Somatic Origins of Prostate Cancer Heterogeneity

Figure 5 from The Germline and Somatic Origins of Prostate Cancer Heterogeneity

<p>Mutational hallmarks of prostate cancer grade. <b>A,</b> A linear model was fit to relate each mutational density measure to ISUP GG using tumor and normal sequencing coverage as covariates. Dot size and color represents the effect size for each ISUP GG as a <i>Z</i>...

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Main Author: Takafumi N. Yamaguchi (19701568) (author)
Other Authors: Kathleen E. Houlahan (19537767) (author), Helen Zhu (20018291) (author), Natalie Kurganovs (21233875) (author), Julie Livingstone (19701595) (author), Natalie S. Fox (21233878) (author), Jiapei Yuan (17782662) (author), Jocelyn Sietsma Penington (21233881) (author), Chol-Hee Jung (21233884) (author), Tommer Schwarz (21233887) (author), Weerachai Jaratlerdsiri (21233890) (author), Job van Riet (15008957) (author), Peter Georgeson (18294822) (author), Stefano Mangiola (15128076) (author), Kodi Taraszka (21233893) (author), Robert Lesurf (21233896) (author), Jue Jiang (21233899) (author), Ken Chow (21233902) (author), Lawrence E. Heisler (17779043) (author), Yu-Jia Shiah (21233905) (author), Susmita G. Ramanand (21233908) (author), Michael J. Clarkson (21233911) (author), Anne Nguyen (21233914) (author), Shadrielle Melijah G. Espiritu (21233917) (author), Ryan Stuchbery (21233920) (author), Richard Jovelin (17779046) (author), Vincent Huang (21233923) (author), Connor Bell (21233926) (author), Edward O’Connor (21233929) (author), Patrick J. McCoy (21233932) (author), Christopher M. Lalansingh (21233935) (author), Marek Cmero (21233938) (author), Adriana Salcedo (21233941) (author), Eva K.F. Chan (14932155) (author), Lydia Y. Liu (21233944) (author), Phillip D. Stricker (21233947) (author), Vinayak Bhandari (21233950) (author), Riana M.S. Bornman (21233953) (author), Dorota H.S. Sendorek (21233956) (author), Andrew Lonie (21233959) (author), Stephenie D. Prokopec (16797700) (author), Michael Fraser (14954695) (author), Justin S. Peters (21233962) (author), Adrien Foucal (21233965) (author), Shingai B.A. Mutambirwa (21233968) (author), Lachlan Mcintosh (21233971) (author), Michèle Orain (21233974) (author), Matthew Wakefield (15048465) (author), Valérie Picard (21233977) (author), Daniel J. Park (21233980) (author), Hélène Hovington (21233983) (author), Michael Kerger (21233986) (author), Alain Bergeron (15097194) (author), Veronica Sabelnykova (21233989) (author), Ji-Heui Seo (14959115) (author), Mark M. Pomerantz (17755179) (author), Noah Zaitlen (21233992) (author), Sebastian M. Waszak (15042965) (author), Alexander Gusev (11666368) (author), Louis Lacombe (21233995) (author), Yves Fradet (15044763) (author), Andrew Ryan (21233998) (author), Amar U. Kishan (19701622) (author), Martijn P. Lolkema (15036135) (author), Joachim Weischenfeldt (21234001) (author), Bernard Têtu (21234004) (author), Anthony J. Costello (21234007) (author), Vanessa M. Hayes (13559468) (author), Rayjean J. Hung (14943811) (author), Housheng H. He (14960919) (author), John D. McPherson (21234010) (author), Bogdan Pasaniuc (15120089) (author), Theodorus van der Kwast (17079167) (author), Anthony T. Papenfuss (10025621) (author), Matthew L. Freedman (14958939) (author), Bernard J. Pope (21234013) (author), Robert G. Bristow (21234016) (author), Ram S. Mani (17782668) (author), Niall M. Corcoran (9250117) (author), Jüri Reimand (10741083) (author), Christopher M. Hovens (21234019) (author), Paul C. Boutros (14954698) (author)
Published: 2025
Subjects:
Cancer
Tumor Biology
Cancer Detection and Diagnosis
Methods and Technology
Biomarkers
Metastasis biomarkers
Computational Methods
Sequence analysis
Genitourinary Cancers
Prostate cancer
Tumor Evolution
Tumor Heterogeneity
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