Presentation 2_FGF2 supports NANOG expression via pyruvate dehydrogenase–dependent histone acetylation under low oxygen conditions.pdf

Presentation 2_FGF2 supports NANOG expression via pyruvate dehydrogenase–dependent histone acetylation under low oxygen conditions.pdf

Introduction<p>The safe and effective application of human pluripotent stem cells (hPSCs) in research and regenerative medicine requires precise control over pluripotency and cell fate. Pluripotency is characterized by high histone acetylation and aerobic glycolysis, while differentiation invo...

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Autor principal: Petr Fojtík (10014185) (author)
Altres autors: Martin Senfluk (22509233) (author), Katerina Holomkova (21813243) (author), Anton Salykin (8994374) (author), Jana Gregorova (22509236) (author), Pavel Smak (22509239) (author), Ondrej Pes (293657) (author), Jan Raska (16034734) (author), Deborah Beckerova (10174135) (author), Monika Stetkova (4488115) (author), Petr Skladal (5640173) (author), Miroslava Sedlackova (710554) (author), Ales Hampl (3852808) (author), Dasa Bohaciakova (6456569) (author), Stjepan Uldrijan (683819) (author), Vladimir Rotrekl (8539998) (author)
Publicat: 2025
Matèries:
Cell Biology
pyruvate dehydrogenase - PDH
histone acetylation
nanog
FGF2
pluripotency
ROS - reactive oxygen species
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