Module-based analysis reveals differences between immune processes in ruptured vs unruptured aneurysms.

Module-based analysis reveals differences between immune processes in ruptured vs unruptured aneurysms.

<p>A: Dendrogram demonstrating the taxonomic relationship between genes with the y-axis representing gene dissimilarity based on the TOM metric. Colour bar representing genes grouped into modules. Grey interspacing represents unclassified genes. B: Boxplots of module meta-gene expression for s...

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Bibliographic Details
Main Author: Alexander P. Landry (6725738) (author)
Other Authors: Michael Balas (7022801) (author), Julian Spears (3952718) (author), Zsolt Zador (3157953) (author)
Published: 2019
Subjects:
Biophysics
Medicine
Cell Biology
Genetics
Molecular Biology
Biotechnology
Infectious Diseases
Biological Sciences not elsewhere classified
Mathematical Sciences not elsewhere classified
drug candidates
aneurysm rupture
rupture-associated mechanisms MHCII antigen processing
intracranial aneurysm rupture
drug repurposing
keratan sulfate catabolism
population-specific gene expression analysis
gene co-expression networks
hypoxia inducible factor
population-specific expression levels
unruptured aneurysm domes
novel drug candidates
Results Network analysis
PSEA
gene expression Background
WGCNA
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