Visualization of example model inputs and empirical data used to inform model inputs.

<p>(A) Example active (deterministic) and latent (stochastic) growth curves based on default values. (B) Conserved nucleotide sites for the example founder sequence (gp120 of DEMB11US006). (C) Epitope probability distribution for HXB2 gp120. After being converted to nucleotides, these position...

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Bibliographic Details
Main Author:	Narmada Sambaturu (4989539) (author)
Other Authors:	Zena Lapp (10804871) (author), Fernando D. K. Tria (9592485) (author), Ethan Romero-Severson (13450323) (author), Carmen Molina-París (4989545) (author), Thomas Leitner (18756) (author)
Published:	2025
Subjects:	Microbiology Genetics Molecular Biology Evolutionary Biology Ecology Immunology Cancer Infectious Diseases Virology Biological Sciences not elsewhere classified summary statistics tested evolving immune response div >< p sequences longitudinally collected defined time points conserved sites fitness sampled virus sequences generate model inputs friendly r package w </ u v </ u host evolution called e </ u simulate virus within host virus sequences also provide functions virus evolution r package </ u simulated sequences virus population virus diversification time individual replicative fitness env </ (< u real sequences simulating within adaptive within world expectation wavess </ three forms selective pressures rigorously validated reference sequence reactivity imposed phylogenies reconstructed new software imulator ), empirical data based model 11 individuals
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Visualization of example model inputs and empirical data used to inform model inputs.

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