Figure 4 – Source Data (TF synaptic transmission and oRRPTF analysis)
<p dir="ltr">This dataset contains the raw numerical values used to generate all panels of Figure 4, which examines thalamofrontal (TF) synaptic transmission following chronic NMDAR hypofunction using optogenetics, whole-cell recordings, and single-unit activity analyses.</p>&l...
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2025
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| _version_ | 1849927637119533056 |
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| author | Jinseon Yu (22598699) |
| author_facet | Jinseon Yu (22598699) |
| author_role | author |
| dc.creator.none.fl_str_mv | Jinseon Yu (22598699) |
| dc.date.none.fl_str_mv | 2025-11-25T04:07:24Z |
| dc.identifier.none.fl_str_mv | 10.6084/m9.figshare.30691859.v1 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/dataset/Figure_4_Source_Data_TF_synaptic_transmission_and_oRRPTF_analysis_/30691859 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biochemistry and cell biology not elsewhere classified TF synapses, oEPSC, oRRPTF, MD stimulation, release probability |
| dc.title.none.fl_str_mv | Figure 4 – Source Data (TF synaptic transmission and oRRPTF analysis) |
| dc.type.none.fl_str_mv | Dataset info:eu-repo/semantics/publishedVersion dataset |
| description | <p dir="ltr">This dataset contains the raw numerical values used to generate all panels of Figure 4, which examines thalamofrontal (TF) synaptic transmission following chronic NMDAR hypofunction using optogenetics, whole-cell recordings, and single-unit activity analyses.</p><p><br></p><p dir="ltr">Included data:</p><p dir="ltr">- Optogenetically evoked EPSCs during 10 Hz stimulation (Panels 4a–d), including peak amplitudes, paired-pulse ratios, and normalized response amplitudes.</p><p dir="ltr">- Single-unit activity recorded in dmPFC during mediodorsal thalamus (MD) electrical stimulation (Panels 4e–h), including spike counts per bin and peri-stimulus histograms at 0.1 Hz and 10 Hz stimulation.</p><p dir="ltr">- Readily releasable pool of TF synapses (oRRP<sub>TF</sub>) during 1 s optogenetic stimulation (Panels 4i–l), including fast component charge, refilling current, nonlinear charge–stimulation power relationships, normalized pool unit (PU) values, and summary measures at saturating intensity.</p><p><br></p><p dir="ltr">Structure:</p><p dir="ltr">- Each worksheet corresponds to a panel or measurement type.</p><p dir="ltr">- All values represent unprocessed raw data directly used to generate the figure.</p><p><br></p><p dir="ltr">This dataset enables full reproduction of the TF synaptic transmission and vesicle pool analyses presented in Figure 4.</p><p><br></p> |
| eu_rights_str_mv | openAccess |
| id | Manara_51489f0f7bed57c7f147d35e7a18ba17 |
| identifier_str_mv | 10.6084/m9.figshare.30691859.v1 |
| network_acronym_str | Manara |
| network_name_str | ManaraRepo |
| oai_identifier_str | oai:figshare.com:article/30691859 |
| publishDate | 2025 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Figure 4 – Source Data (TF synaptic transmission and oRRPTF analysis)Jinseon Yu (22598699)Biochemistry and cell biology not elsewhere classifiedTF synapses, oEPSC, oRRPTF, MD stimulation, release probability<p dir="ltr">This dataset contains the raw numerical values used to generate all panels of Figure 4, which examines thalamofrontal (TF) synaptic transmission following chronic NMDAR hypofunction using optogenetics, whole-cell recordings, and single-unit activity analyses.</p><p><br></p><p dir="ltr">Included data:</p><p dir="ltr">- Optogenetically evoked EPSCs during 10 Hz stimulation (Panels 4a–d), including peak amplitudes, paired-pulse ratios, and normalized response amplitudes.</p><p dir="ltr">- Single-unit activity recorded in dmPFC during mediodorsal thalamus (MD) electrical stimulation (Panels 4e–h), including spike counts per bin and peri-stimulus histograms at 0.1 Hz and 10 Hz stimulation.</p><p dir="ltr">- Readily releasable pool of TF synapses (oRRP<sub>TF</sub>) during 1 s optogenetic stimulation (Panels 4i–l), including fast component charge, refilling current, nonlinear charge–stimulation power relationships, normalized pool unit (PU) values, and summary measures at saturating intensity.</p><p><br></p><p dir="ltr">Structure:</p><p dir="ltr">- Each worksheet corresponds to a panel or measurement type.</p><p dir="ltr">- All values represent unprocessed raw data directly used to generate the figure.</p><p><br></p><p dir="ltr">This dataset enables full reproduction of the TF synaptic transmission and vesicle pool analyses presented in Figure 4.</p><p><br></p>2025-11-25T04:07:24ZDatasetinfo:eu-repo/semantics/publishedVersiondataset10.6084/m9.figshare.30691859.v1https://figshare.com/articles/dataset/Figure_4_Source_Data_TF_synaptic_transmission_and_oRRPTF_analysis_/30691859CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/306918592025-11-25T04:07:24Z |
| spellingShingle | Figure 4 – Source Data (TF synaptic transmission and oRRPTF analysis) Jinseon Yu (22598699) Biochemistry and cell biology not elsewhere classified TF synapses, oEPSC, oRRPTF, MD stimulation, release probability |
| status_str | publishedVersion |
| title | Figure 4 – Source Data (TF synaptic transmission and oRRPTF analysis) |
| title_full | Figure 4 – Source Data (TF synaptic transmission and oRRPTF analysis) |
| title_fullStr | Figure 4 – Source Data (TF synaptic transmission and oRRPTF analysis) |
| title_full_unstemmed | Figure 4 – Source Data (TF synaptic transmission and oRRPTF analysis) |
| title_short | Figure 4 – Source Data (TF synaptic transmission and oRRPTF analysis) |
| title_sort | Figure 4 – Source Data (TF synaptic transmission and oRRPTF analysis) |
| topic | Biochemistry and cell biology not elsewhere classified TF synapses, oEPSC, oRRPTF, MD stimulation, release probability |