Image_3_Glutamine Metabolism Drives Growth in Advanced Hormone Receptor Positive Breast Cancer.TIF

Image_3_Glutamine Metabolism Drives Growth in Advanced Hormone Receptor Positive Breast Cancer.TIF

<p>Dependence on the glutamine pathway is increased in advanced breast cancer cell models and tumors regardless of hormone receptor status or function. While 70% of breast cancers are estrogen receptor positive (ER+) and depend on estrogen signaling for growth, advanced ER+ breast cancers grow...

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Bibliographic Details
Main Author: Diane M. Demas (7121717) (author)
Other Authors: Susan Demo (191707) (author), Yassi Fallah (7121720) (author), Robert Clarke (17961) (author), Kenneth P. Nephew (212536) (author), Sandra Althouse (5168195) (author), George Sandusky (3755482) (author), Wei He (131453) (author), Ayesha N. Shajahan-Haq (7121723) (author)
Published: 2019
Subjects:
Cancer
Cancer Cell Biology
Cancer Diagnosis
Cancer Genetics
Cancer Therapy (excl. Chemotherapy and Radiation Therapy)
Chemotherapy
Haematological Tumours
Molecular Targets
Radiation Therapy
Solid Tumours
Oncology and Carcinogenesis not elsewhere classified
breast cancer
endocrine resistance
glutamine metabolism
mTOR
CB-839
everolimus
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