Supplementary Table S9 from <i>In Vivo</i> Screening Unveils Pervasive RNA-Binding Protein Dependencies in Leukemic Stem Cells and Identifies ELAVL1 as a Therapeutic Target

<p>Table S9 shows the (a) differentially expressed transcripts and (b) altered pathways as identified by GSEA from the ELAVL1 knockdown human primary AML RNA-sequencing data set.</p>

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awdur: Ana Vujovic (15207479) (author)
Awduron Eraill: Laura de Rooij (15207482) (author), Ava Keyvani Chahi (15207485) (author), He Tian Chen (15207488) (author), Brian A. Yee (15207491) (author), Sampath K. Loganathan (15121740) (author), Lina Liu (15207494) (author), Derek C.H. Chan (15207497) (author), Amanda Tajik (15207500) (author), Emily Tsao (15207503) (author), Steven Moreira (14937143) (author), Pratik Joshi (15207506) (author), Joshua Xu (15207509) (author), Nicholas Wong (15207512) (author), Zaldy Balde (15207515) (author), Soheil Jahangiri (15207518) (author), Sasan Zandi (15207521) (author), Stefan Aigner (15207524) (author), John E. Dick (14937554) (author), Mark D. Minden (14961936) (author), Daniel Schramek (15121764) (author), Gene W. Yeo (15207527) (author), Kristin J. Hope (15207530) (author)
Cyhoeddwyd: 2025
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author Ana Vujovic (15207479)
author2 Laura de Rooij (15207482)
Ava Keyvani Chahi (15207485)
He Tian Chen (15207488)
Brian A. Yee (15207491)
Sampath K. Loganathan (15121740)
Lina Liu (15207494)
Derek C.H. Chan (15207497)
Amanda Tajik (15207500)
Emily Tsao (15207503)
Steven Moreira (14937143)
Pratik Joshi (15207506)
Joshua Xu (15207509)
Nicholas Wong (15207512)
Zaldy Balde (15207515)
Soheil Jahangiri (15207518)
Sasan Zandi (15207521)
Stefan Aigner (15207524)
John E. Dick (14937554)
Mark D. Minden (14961936)
Daniel Schramek (15121764)
Gene W. Yeo (15207527)
Kristin J. Hope (15207530)
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author_facet Ana Vujovic (15207479)
Laura de Rooij (15207482)
Ava Keyvani Chahi (15207485)
He Tian Chen (15207488)
Brian A. Yee (15207491)
Sampath K. Loganathan (15121740)
Lina Liu (15207494)
Derek C.H. Chan (15207497)
Amanda Tajik (15207500)
Emily Tsao (15207503)
Steven Moreira (14937143)
Pratik Joshi (15207506)
Joshua Xu (15207509)
Nicholas Wong (15207512)
Zaldy Balde (15207515)
Soheil Jahangiri (15207518)
Sasan Zandi (15207521)
Stefan Aigner (15207524)
John E. Dick (14937554)
Mark D. Minden (14961936)
Daniel Schramek (15121764)
Gene W. Yeo (15207527)
Kristin J. Hope (15207530)
author_role author
dc.creator.none.fl_str_mv Ana Vujovic (15207479)
Laura de Rooij (15207482)
Ava Keyvani Chahi (15207485)
He Tian Chen (15207488)
Brian A. Yee (15207491)
Sampath K. Loganathan (15121740)
Lina Liu (15207494)
Derek C.H. Chan (15207497)
Amanda Tajik (15207500)
Emily Tsao (15207503)
Steven Moreira (14937143)
Pratik Joshi (15207506)
Joshua Xu (15207509)
Nicholas Wong (15207512)
Zaldy Balde (15207515)
Soheil Jahangiri (15207518)
Sasan Zandi (15207521)
Stefan Aigner (15207524)
John E. Dick (14937554)
Mark D. Minden (14961936)
Daniel Schramek (15121764)
Gene W. Yeo (15207527)
Kristin J. Hope (15207530)
dc.date.none.fl_str_mv 2025-11-24T22:02:21Z
dc.identifier.none.fl_str_mv 10.1158/2643-3230.30698679
dc.relation.none.fl_str_mv https://figshare.com/articles/dataset/Supplementary_Table_S9_from_i_In_Vivo_i_Screening_Unveils_Pervasive_RNA-Binding_Protein_Dependencies_in_Leukemic_Stem_Cells_and_Identifies_ELAVL1_as_a_Therapeutic_Target/30698679
dc.rights.none.fl_str_mv CC BY
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Cancer
Cancer Biology
Molecular and Cellular Biology
Therapeutic Research and Development
Methods and Technology
Drug Targets
Oncoprotein & tumor suppressor drug targets
Gene Regulation
Posttranscriptional and translational control
Hematological Cancers
Leukemias
Oncogenes & Tumor Suppressors
Oncogenes
Preclinical Models
Xenograft models
Small Molecule Agents
Stem Cell Biology
Cancer stem cells
Hematopoiesis
dc.title.none.fl_str_mv Supplementary Table S9 from <i>In Vivo</i> Screening Unveils Pervasive RNA-Binding Protein Dependencies in Leukemic Stem Cells and Identifies ELAVL1 as a Therapeutic Target
dc.type.none.fl_str_mv Dataset
info:eu-repo/semantics/publishedVersion
dataset
description <p>Table S9 shows the (a) differentially expressed transcripts and (b) altered pathways as identified by GSEA from the ELAVL1 knockdown human primary AML RNA-sequencing data set.</p>
eu_rights_str_mv openAccess
id Manara_554ae1e8cfcb80743323dedb7bcf03c4
identifier_str_mv 10.1158/2643-3230.30698679
network_acronym_str Manara
network_name_str ManaraRepo
oai_identifier_str oai:figshare.com:article/30698679
publishDate 2025
repository.mail.fl_str_mv
repository.name.fl_str_mv
repository_id_str
rights_invalid_str_mv CC BY
spelling Supplementary Table S9 from <i>In Vivo</i> Screening Unveils Pervasive RNA-Binding Protein Dependencies in Leukemic Stem Cells and Identifies ELAVL1 as a Therapeutic TargetAna Vujovic (15207479)Laura de Rooij (15207482)Ava Keyvani Chahi (15207485)He Tian Chen (15207488)Brian A. Yee (15207491)Sampath K. Loganathan (15121740)Lina Liu (15207494)Derek C.H. Chan (15207497)Amanda Tajik (15207500)Emily Tsao (15207503)Steven Moreira (14937143)Pratik Joshi (15207506)Joshua Xu (15207509)Nicholas Wong (15207512)Zaldy Balde (15207515)Soheil Jahangiri (15207518)Sasan Zandi (15207521)Stefan Aigner (15207524)John E. Dick (14937554)Mark D. Minden (14961936)Daniel Schramek (15121764)Gene W. Yeo (15207527)Kristin J. Hope (15207530)CancerCancer BiologyMolecular and Cellular BiologyTherapeutic Research and DevelopmentMethods and TechnologyDrug TargetsOncoprotein & tumor suppressor drug targetsGene RegulationPosttranscriptional and translational controlHematological CancersLeukemiasOncogenes & Tumor SuppressorsOncogenesPreclinical ModelsXenograft modelsSmall Molecule AgentsStem Cell BiologyCancer stem cellsHematopoiesis<p>Table S9 shows the (a) differentially expressed transcripts and (b) altered pathways as identified by GSEA from the ELAVL1 knockdown human primary AML RNA-sequencing data set.</p>2025-11-24T22:02:21ZDatasetinfo:eu-repo/semantics/publishedVersiondataset10.1158/2643-3230.30698679https://figshare.com/articles/dataset/Supplementary_Table_S9_from_i_In_Vivo_i_Screening_Unveils_Pervasive_RNA-Binding_Protein_Dependencies_in_Leukemic_Stem_Cells_and_Identifies_ELAVL1_as_a_Therapeutic_Target/30698679CC BYinfo:eu-repo/semantics/openAccessoai:figshare.com:article/306986792025-11-24T22:02:21Z
spellingShingle Supplementary Table S9 from <i>In Vivo</i> Screening Unveils Pervasive RNA-Binding Protein Dependencies in Leukemic Stem Cells and Identifies ELAVL1 as a Therapeutic Target
Ana Vujovic (15207479)
Cancer
Cancer Biology
Molecular and Cellular Biology
Therapeutic Research and Development
Methods and Technology
Drug Targets
Oncoprotein & tumor suppressor drug targets
Gene Regulation
Posttranscriptional and translational control
Hematological Cancers
Leukemias
Oncogenes & Tumor Suppressors
Oncogenes
Preclinical Models
Xenograft models
Small Molecule Agents
Stem Cell Biology
Cancer stem cells
Hematopoiesis
status_str publishedVersion
title Supplementary Table S9 from <i>In Vivo</i> Screening Unveils Pervasive RNA-Binding Protein Dependencies in Leukemic Stem Cells and Identifies ELAVL1 as a Therapeutic Target
title_full Supplementary Table S9 from <i>In Vivo</i> Screening Unveils Pervasive RNA-Binding Protein Dependencies in Leukemic Stem Cells and Identifies ELAVL1 as a Therapeutic Target
title_fullStr Supplementary Table S9 from <i>In Vivo</i> Screening Unveils Pervasive RNA-Binding Protein Dependencies in Leukemic Stem Cells and Identifies ELAVL1 as a Therapeutic Target
title_full_unstemmed Supplementary Table S9 from <i>In Vivo</i> Screening Unveils Pervasive RNA-Binding Protein Dependencies in Leukemic Stem Cells and Identifies ELAVL1 as a Therapeutic Target
title_short Supplementary Table S9 from <i>In Vivo</i> Screening Unveils Pervasive RNA-Binding Protein Dependencies in Leukemic Stem Cells and Identifies ELAVL1 as a Therapeutic Target
title_sort Supplementary Table S9 from <i>In Vivo</i> Screening Unveils Pervasive RNA-Binding Protein Dependencies in Leukemic Stem Cells and Identifies ELAVL1 as a Therapeutic Target
topic Cancer
Cancer Biology
Molecular and Cellular Biology
Therapeutic Research and Development
Methods and Technology
Drug Targets
Oncoprotein & tumor suppressor drug targets
Gene Regulation
Posttranscriptional and translational control
Hematological Cancers
Leukemias
Oncogenes & Tumor Suppressors
Oncogenes
Preclinical Models
Xenograft models
Small Molecule Agents
Stem Cell Biology
Cancer stem cells
Hematopoiesis