Targeted screen of 20 conserved neuronal RBPs reveals eight novel associative memory regulators.

(A) Short-term and intermediate-term associative memory (STM and ITM) assay workflow using adult-only RNAi knockdown. Worms that are neuronally sensitive to RNAi, LC108(usIS69[myo-2p::mCherry + unc119p::sid-1]), wer...

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Bibliographic Details
Main Author:	Ashley N. Hayden (19871128) (author)
Other Authors:	Katie L. Brandel (19871131) (author), Edward W. Pietryk (5777888) (author), Paul R. Merlau (19871134) (author), Priyadharshini Vijayakumar (19871137) (author), Emily J. Leptich (19871140) (author), Elizabeth S. Gaytan (19871143) (author), Meredith I. Williams (19871146) (author), Connie W. Ni (19871149) (author), Hsiao-Tuan Chao (4454008) (author), Jill A. Rosenfeld (9606199) (author), Rachel N. Arey (19871152) (author)
Published:	2024
Subjects:	Biochemistry Neuroscience Pharmacology Evolutionary Biology Immunology Cancer Mental Health Infectious Diseases Biological Sciences not elsewhere classified test evolutionary conservation single nucleotide variants potential new source behavioral screening reveals potential functional significance leveraging human datasets ></ u >< reveal memory regulators div >< p x </ u b </ u identifies ybx dysfunction binding protein required 20 conserved rbps u >< unknown significance rbp dysfunction human genome conserved residue binding proteins ybxs </ ybx3 </ legans </ elegans </ e </ c </ 3 </ study highlights regulate translation rbp family promote memory neurological symptoms neurological phenotypes neurological disorders nervous system memory ability key symptom functionally replace cognitive impairments closest ortholog associative learning 000 rbps
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Targeted screen of 20 conserved neuronal RBPs reveals eight novel associative memory regulators.

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