Expression of UPR- and inflammation-associated genes and genes associated with pathological hypertrophy following swim training.

Expression of UPR- and inflammation-associated genes and genes associated with pathological hypertrophy following swim training.

<p>qPCR was used to assess (A) the expression of ER stress- and inflammation-associated genes and (B) the pathological hypertrophy-associated genes in sedentary (rest) and swim-trained Wt, <i>Atf6</i><sup>-/-</sup>, and <i>Atf6b</i><sup>-/-</sup>...

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Bibliographic Details
Main Author: Emery Davis (21011631) (author)
Other Authors: Mohammad-Reza Shokri (11542533) (author), Mary B. Rowland (21011634) (author), Thomas York (21011637) (author), Caroline T. Cohen (21011640) (author), Anna Grace Johnson (21011643) (author), Patrick E. Moore (21011646) (author), Saige Schweitzer (21011649) (author), Jon Sin (550460) (author), Chuong Bui (2336341) (author), Robert N. Correll (21011652) (author)
Published: 2025
Subjects:
Biochemistry
Cell Biology
Genetics
Molecular Biology
Physiology
Developmental Biology
Cancer
whole body gene
showed enhanced phosphorylation
regulated kinase 1
reduced fractional shortening
downstream upr signaling
displayed ventricular dilation
found differential roles
atf6 &# 946
atf6 &# 945
induced physiological hypertrophy
physiological hypertrophy
functional roles
pathological hypertrophy
type mice
swim training
previously described
hemodynamic stress
extracellular signal
compensatory remodeling
20 days
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