Advancing DNA and RNA Modification Detection via Nanopore Sequencing

DNA/RNA modifications are crucial for biological processes. To understand their regulatory mechanisms, precise mapping and quantification of these modifications are essential. Although next-generation sequencing can detect the location and stoichiometry of modifications, complex treatments are requi...

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Bibliografske podrobnosti
Glavni avtor:	Bo He (367100) (author)
Drugi avtorji:	Yu Fan (111503) (author), Jizhou Liu (5898005) (author), Yuting Chen (151583) (author), Jinmin Yang (13946559) (author), Huifen Xiang (11780123) (author), Jinying Peng (645608) (author), Chengqi Yi (793646) (author)
Izdano:	2025
Teme:	Biophysics Biochemistry Medicine Genetics Molecular Biology Pharmacology Sociology Inorganic Chemistry Space Science Biological Sciences not elsewhere classified Physical Sciences not elsewhere classified time modification detection suggest future directions thus preserving dna rna modification information gained widespread applications nanopore sequencing eliminates nanopore sequencing world applications advancing dna generation sequencing rna modifications regulatory mechanisms range analysis quantified directly precise mapping perspective introduces pcr amplification molecule level hindering efficiency current challenges critically examines complex treatments biological processes although next additional treatment
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Advancing DNA and RNA Modification Detection via Nanopore Sequencing

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