TH5487 decreases RSV-induced release of lactose dehydrogenase (LDH).

<p>hSAECs were treated with indicated concentrations of TH5487, O8, or TH2840 post RSV inoculum (MOI = 1). Cell culture medium was harvested at 24 hpi to perform LDH assay according to the manufacturer’s instruction. The absorbance at 450 nm was determined using a microplate reader (Synergy H1...

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Main Author:	Lang Pan (5145221) (author)
Other Authors:	Ke Wang (82395) (author), Wenjing Hao (529440) (author), Yaoyao Xue (12836780) (author), Xu Zheng (296676) (author), Ritwika S. Basu (19859948) (author), Tapas K. Hazra (17810975) (author), Azharul Islam (597435) (author), Yashoda Hosakote (19859951) (author), Bing Tian (39960) (author), Matthieu G. Gagnon (7935944) (author), Xueqing Ba (397240) (author), Istvan Boldogh (16539) (author)
Published:	2024
Subjects:	Biochemistry Medicine Microbiology Cell Biology Genetics Molecular Biology Evolutionary Biology Cancer Mental Health Infectious Diseases Virology Environmental Sciences not elsewhere classified Biological Sciences not elsewhere classified reading function could reactive oxygen species maintain genetic fidelity especially within guanine respiratory tract infections ogg1 binding sites rsv ), along ros ), respiratory diseases ogg1 ). rsv rna rsv antigenome significantly contributes ros activity rna immunoprecipitation rich sequences results underscore predominantly found pathogens induce oxidative challenges novel strategy investigation revealed incidental byproduct global incidence generation sequencing crucial role associated rna
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TH5487 decreases RSV-induced release of lactose dehydrogenase (LDH).

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