Co-Catalytic Coupling of Alkyl Halides and Alkenes: the Curious Role of Lutidine

Co-Catalytic Coupling of Alkyl Halides and Alkenes: the Curious Role of Lutidine

Continuous pressure to shorten synthetic sequences along with the concomitant expansion of scope makes the use of alkyl bromides, chlorides, and oxygen based leaving groups- which are abundant and readily available feedstocks, highly attractive for C–C bond synthesis. However, selective activation o...

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Bibliographic Details
Main Author: Roshini Hanumanthu (18853250) (author)
Other Authors: Parul Sharma (6100181) (author), Avery Ethridge (17067395) (author), Jimmie D. Weaver (1666147) (author)
Published: 2025
Subjects:
Biochemistry
Medicine
Sociology
Cancer
Infectious Diseases
Environmental Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
readily available feedstocks
improved reaction profiles
halogen atom transfer
facilitate electron transfer
lutidinium iodide salt
lutidine continuous pressure
tertiary alkyl radicals
respective alkyl chlorides
lutidinium radical
alkyl halides
visible light
selective activation
scope makes
reduction potentials
nucleophilic exchange
method relies
investigation revealed
highly attractive
curious role
critical cocatalyst
concomitant expansion
catalytic coupling
alkyl bromides
access primary
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