Co-Catalytic Coupling of Alkyl Halides and Alkenes: the Curious Role of Lutidine

Continuous pressure to shorten synthetic sequences along with the concomitant expansion of scope makes the use of alkyl bromides, chlorides, and oxygen based leaving groups- which are abundant and readily available feedstocks, highly attractive for C–C bond synthesis. However, selective activation o...

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Bibliographic Details
Main Author:	Roshini Hanumanthu (18853250) (author)
Other Authors:	Parul Sharma (6100181) (author), Avery Ethridge (17067395) (author), Jimmie D. Weaver (1666147) (author)
Published:	2025
Subjects:	Biochemistry Medicine Sociology Cancer Infectious Diseases Environmental Sciences not elsewhere classified Chemical Sciences not elsewhere classified readily available feedstocks improved reaction profiles halogen atom transfer facilitate electron transfer lutidinium iodide salt lutidine continuous pressure tertiary alkyl radicals respective alkyl chlorides lutidinium radical alkyl halides visible light selective activation scope makes reduction potentials nucleophilic exchange method relies investigation revealed highly attractive curious role critical cocatalyst concomitant expansion catalytic coupling alkyl bromides access primary
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Co-Catalytic Coupling of Alkyl Halides and Alkenes: the Curious Role of Lutidine

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