Examples for potentially CTF modifying pathogenic variants.

Examples for potentially CTF modifying pathogenic variants.

<p>a) Illustration of <i>SMC1A</i> function. Interact with <i>SMC3</i> and other proteins to create the cohesin complex and trap sister chromatids within it. <i>SMC1A</i> and <i>SMC3</i> interact through the hinge domain of both proteins. b) <...

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Bibliographic Details
Main Author:	Tal Gutman (20477487) (author)
Other Authors:	Tamir Tuller (123492) (author)
Published:	2024
Subjects:	Biophysics Biochemistry Genetics Molecular Biology Pharmacology Cancer Virology Biological Sciences not elsewhere classified leveraging current knowledge extensive research efforts translational folding trajectory driven transporter capable clinical cohort analyses potentially impacts p div >< p glycoprotein efflux pump disease related variants elucidate potential mechanisms modify mrna folding gene regulatory mechanisms genetic variants within gene expression process cancer cells via mrna folding genetic variants molecular mechanisms glycoprotein expression clinical outcomes mrna structure cancer prognosis cancer patients glycoprotein levels glycoprotein conformation three variants various cancers treatment resistance t3435c </ t2677g </ t1236c </ systematically evaluate systematically applied remarkably contradictory protein expression principal stages potential impact mdr1 </ identify hundreds functional consequences functional activity driven approach diverse array
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