Long-Term Single-Particle Tracking of Membrane Proteins Enabled by Upconversion Alkaline-Earth Nanoprobes

Single-particle tracking (SPT) provides mechanistic insights into individual biomolecules but suffers from the limited photostability of conventional probes. Upconversion SPT (uSPT), employing lanthanide-doped nanoparticles (UCNPs) as probes, enables extended imaging durations; however, its broader...

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التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Huan Ling (18150399) (author)
مؤلفون آخرون:	Jinyang Liu (2060833) (author), Fan Ding (302565) (author), Fei Zhao (183673) (author), Song Chen (69646) (author), Wenrui Zhang (1486636) (author), Yunxiang Zhang (1301400) (author), Qian Liu (135614) (author)
منشور في:	2025
الموضوعات:	Biophysics Medicine Cell Biology Biotechnology Space Science Physical Sciences not elsewhere classified provides mechanistic insights membrane proteins enabled engineered ucnps exhibit earth nanoprobes single regulating egfr dynamics term single earth materials upconversion alkaline reversible transitions particle tracking nanoparticle size motional states motional heterogeneity markedly altered limited photostability individual egfr individual biomolecules fold increase findings demonstrate enhanced luminescence doped nanoparticles critical role conventional sodium compact dimensions broader application based counterparts based alkaline
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Long-Term Single-Particle Tracking of Membrane Proteins Enabled by Upconversion Alkaline-Earth Nanoprobes

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