Cases with clonal MMR deficiencies.

<div><p>Microsatellite instability (MSI) is an important genomic biomarker for cancer diagnosis and treatment, and sequencing-based approaches are often applied to identify MSI because of its fastness and efficiency. These approaches, however, may fail to identify MSI on one or more sub-...

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التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Yuqian Liu (1413763) (author)
مؤلفون آخرون:	Yan Chen (4308) (author), Huanwen Wu (697595) (author), Xuanping Zhang (748046) (author), Yuqi Wang (270190) (author), Xin Yi (180644) (author), Zhiyong Liang (580570) (author), Jiayin Wang (447066) (author)
منشور في:	2024
الموضوعات:	Biotechnology Cancer Plant Biology Biological Sciences not elsewhere classified Mathematical Sciences not elsewhere classified Information Systems not elsewhere classified subtle generative model simulation datasets concerning sample &# 8217 integrative bayesian method important genomic biomarker impact factors demonstrated exhibiting positive responses 16 patients diagnosed integrated deconvolution model scmsi reported msi unsuitable treatments testing results scmsi provides satellite status optimized division often applied new way microsatellite status may fail length distribution high degree heuristic algorithm findings matched exponentially increased erroneous diagnoses endometrial cancer efficient estimation detecting msi computational cost clonal structure clonal msi clonal micro cancer diagnosis adhere optimally accurately inferring
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Cases with clonal MMR deficiencies.

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