4sU-seq Signal at Putative Enhancers in Day 3 and 4 ADE Populations.

4sU-seq Signal at Putative Enhancers in Day 3 and 4 ADE Populations.

<p>Data table of normalised 4sU-seq signal at putative enhancer ‘peaks’ identified in Day 3 and 4 ADE populations by the dREG algorithm. Regions are annotated according to the mm9 genome assembly. Proximity of dREG peaks to the nearest neighbouring gene (RefSeq annotation) within the specified...

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Main Author: Jurriaan Jochem Hölzenspies (20642889) (author)
Other Authors: Dipta Sengupta (20642892) (author), Wendy Anne Bickmore (20642895) (author), Joshua Mark Brickman (20642898) (author), Robert Scott Illingworth (20642901) (author)
Published: 2025
Subjects:
Cell Biology
Genetics
Developmental Biology
Environmental Sciences not elsewhere classified
Biological Sciences not elsewhere classified
provided key insights
prc2 promotes canalisation
embryonic stem cells
developmental transcriptional response
process termed gastrulation
early developmental failure
polycomb proteins manifests
polycomb proteins
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transcriptional activation
polycomb system
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early gastrulation
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transcription factors
subordinate rather
perturbed due
mouse models
molecular function
lineage fidelity
genetic circuitry
gene repression
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epigenetic factors
deleterious mutations
delayed relative
chromatin modifiers
chemical inhibition
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