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  • X-ray crystallographic structu...
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X-ray crystallographic structure of the Aβ oligomer mimic, 2AT-L (PDB 7U4P).

X-ray crystallographic structure of the Aβ oligomer mimic, 2AT-L (PDB 7U4P).

<p>X-ray crystallographic structure of the Aβ oligomer mimic, 2AT-L (PDB 7U4P).</p>

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awdur: Sarah M. Ruttenberg (22208828) (author)
Awduron Eraill: Rakia Dhaoui (9389669) (author), Adam G. Kreutzer (1673791) (author), James S. Nowick (1272555) (author)
Cyhoeddwyd: 2025
Pynciau:
Biochemistry
Microbiology
Cell Biology
Genetics
Molecular Biology
Neuroscience
Biotechnology
Evolutionary Biology
Developmental Biology
Cancer
Mental Health
Infectious Diseases
Virology
Computational Biology
Chemical Sciences not elsewhere classified
tem studies indicate
protects human ipsc
oligomer mimic composed
identifying structural features
xlink "> 2at
three disulfide bonds
simply sequester monomeric
laboratory recently reported
exhibit neuroprotective effects
div >< p
ad brain tissue
&# 946 ;.
stoichiometric ratios suggests
l </ sub
&# 946
stoichiometric ratios
molar ratios
triangular fashion
structurally defined
moderately selective
many aspects
important tools
diffuse peripheries
derived neurons
current study
covalently stabilized
binds toxic
aβ peptide
alzheimer ’
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Eitemau Tebyg

  • pAb<sub>2AT-L</sub> inhibits Aβ<sub>42</sub> fibril formation as visualized by TEM imaging.
    gan: Sarah M. Ruttenberg (22208828)
    Cyhoeddwyd: (2025)
  • pAb<sub>2AT-L</sub> delays fibril formation of Aβ<sub>42</sub>.
    gan: Sarah M. Ruttenberg (22208828)
    Cyhoeddwyd: (2025)
  • pAb<sub>2AT-L</sub> protects i<sup>3</sup>Neurons from Aβ<sub>42</sub>-mediated toxicity as measured by ATP production and LDH release.
    gan: Sarah M. Ruttenberg (22208828)
    Cyhoeddwyd: (2025)
  • Aβ<sub>42</sub> toxicity in i<sup>3</sup>Neurons.
    gan: Sarah M. Ruttenberg (22208828)
    Cyhoeddwyd: (2025)
  • <b>Depth-Dependence of Soil Stoichiometry Decoupling in China’s Croplands over the Last Four Decades</b>
    gan: Andong Cai (10329365)
    Cyhoeddwyd: (2025)

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