Heart bacterial burden in mice infected with MRSA wild-type, Δ<i>yqhG</i>, and complemented strains.

Heart bacterial burden in mice infected with MRSA wild-type, Δ<i>yqhG</i>, and complemented strains.

<p>Heart bacterial burden in mice infected with MRSA wild-type, Δ<i>yqhG</i>, and complemented strains.</p>

Αποθηκεύτηκε σε:

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριος συγγραφέας:	Jianhua Liao (1393228) (author)
Άλλοι συγγραφείς:	Jun Cheng (194158) (author), Baoqing Liu (1508821) (author), Yuzhi Shao (22683349) (author), Chunyan Meng (5993228) (author)
Έκδοση:	2025
Θέματα:	Medicine Microbiology Cell Biology Biotechnology Evolutionary Biology Ecology Science Policy Infectious Diseases Virology Environmental Sciences not elsewhere classified Biological Sciences not elsewhere classified therapeutic strategies aimed novel therapeutic approaches murine infection model div >< p defense mechanisms employed conserved gene encoding compromising membrane stability affect biofilm formation staphylococcus aureus </ reduced bacterial burden improved host survival maintaining mrsa ’ oxidative stress resistance yqhg </ withstand host reduced motility oxidative stress increasing resistance stress adaptation potential target periplasmic protein mrsa virulence mrsa pathogenesis key determinant infected organs increased sensitivity imposed stresses growing prevalence findings highlight existing antibiotics critical need attenuates virulence
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Παρόμοια τεκμήρια

Kidney bacterial burden in mice infected with MRSA wild-type, Δ<i>yqhG</i>, and complemented strains.
ανά: Jianhua Liao (1393228)
Έκδοση: (2025)

Survival data of BALB/c mice infected with MRSA wild-type, Δ<i>yqhG</i>, and complemented strains.
ανά: Jianhua Liao (1393228)
Έκδοση: (2025)

Crystal violet quantification of biofilm formation in MRSA wild-type, ΔyqhG, and complemented strains.
ανά: Jianhua Liao (1393228)
Έκδοση: (2025)

Spleen bacterial burden in mice infected with MRSA wild-type, ΔyqhG, and complemented strains.
ανά: Jianhua Liao (1393228)
Έκδοση: (2025)

Liver bacterial burden in mice infected with MRSA wild-type, ΔyqhG, and complemented strains.
ανά: Jianhua Liao (1393228)
Έκδοση: (2025)

Optical density measurements of MRSA wild-type, Δ<i>yqhG</i>, and complemented strains during <i>in vitro</i> growth.
ανά: Jianhua Liao (1393228)
Έκδοση: (2025)

Amount of PSMs (μg/1mL culture) in MRSA wild-type, ΔyqhG, and complemented strains.
ανά: Jianhua Liao (1393228)
Έκδοση: (2025)

Surface motility of the <i>yqhG</i> mutant.
ανά: Jianhua Liao (1393228)
Έκδοση: (2025)

Membrane integrity in the <i>yqhG</i> mutant.
ανά: Jianhua Liao (1393228)
Έκδοση: (2025)

Quantification of cell-associated PSMs in wild-type, Δ<i>yqhG</i>, and complemented strains. Cell-associated PSMs were extracted from bacterial pellets using 6 M guanidine hydrochloride and quantified by reversed-phase HPLC. The Δ<i>yqhG</i> mutant exhibited a significant reduction in surface-bound PSMs compared with the wild-type strain, whereas complementation restored PSM levels to near wild-type values. Data represent mean ± s.e.m. from three independent experiments. Statistical analysis was performed using one-way ANOVA; *<i>P</i> < 0.05, ns, not significant.
ανά: Jianhua Liao (1393228)
Έκδοση: (2025)

Oxidative stress resistance of the <i>yqhG</i> mutant.
ανά: Jianhua Liao (1393228)
Έκδοση: (2025)

YqhG is required for systemic virulence but not for <i>in vitro</i> growth.
ανά: Jianhua Liao (1393228)
Έκδοση: (2025)

Biofilm formation in MRSA strains.
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Έκδοση: (2025)

Primers Used in This Study.
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Έκδοση: (2025)

Bacterial Strains and Plasmids Used in This Study.
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Έκδοση: (2025)

Viable CFU counts following hydrogen peroxide exposure.
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Έκδοση: (2025)

Colony diameter measurements from soft agar motility assays.
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Έκδοση: (2025)

SYTOX Green fluorescence measurements for membrane permeability assessment.
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Έκδοση: (2025)

Table 1_Hard to jump: host shifts appear unlikely in a T4-like phage evolved in the lab.xlsx
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Supplementary file 1_Hard to jump: host shifts appear unlikely in a T4-like phage evolved in the lab.docx
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Protocatechuic Acid alleviates D-gal-induced renal senescence and injury in mice by regulating taurine metabolism
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Data Sheet 1_Melatonin mitigates cadmium-induced oxidative damage and modulates polysaccharide biosynthesis in Bletilla striata.docx
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Effects of <i>T. gondii</i> infection on rat gut microbiota diversity.
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Untargeted serum metabolomics analysis before and after <i>T. gondii</i> infection.
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Functional analysis of the intestinal microbial community following <i>T. gondii</i> infection.
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Composition of intestinal microbial communities in the large intestine of rats before and after <i>T. gondii</i> infection.
ανά: Ji-Xin Zhao (22056386)
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Composition of intestinal microbial communities in the small intestine of rats before and after <i>T. gondii</i> infection.
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Έκδοση: (2025)

Differential metabolite results, listing metabolites with significant changes across treatment groups, including fold changes, and <i>p</i>-values.
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Έκδοση: (2025)

Correlation network between intestinal bacterial species and differential serum metabolites.
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Έκδοση: (2025)

KEGG pathway enrichment analysis of differential serum metabolites.
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Έκδοση: (2025)

Spearman correlation analysis between gut microbial taxa and circulating metabolites, detailing correlation coefficients, significance values, and taxon–metabolite pairings indicative of microbiome–host metabolic interactions.
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Έκδοση: (2025)

Pathway enrichment analysis of differential metabolites, highlighting significantly impacted metabolic pathways and associated enrichment statistics based on KEGG or other pathway databases.
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Orthogonal partial least squares-discriminant analysis (OPLS-DA) of serum metabolomics data.
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Quality control assessment of serum metabolomics data.
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Heatmap of enriched KEGG pathways across samples, illustrating variations in pathway abundance.
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Graphical abstract.
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The U sequence method.
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Provisional study schedule of MUSIBOT.
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