24-OHC facilitates the propagation of α-Syn pathology and mitochondrial dysfunction.

24-OHC facilitates the propagation of α-Syn pathology and mitochondrial dysfunction.

<p><b>(A, B)</b> α-Syn-GFP HEK293 cells were transduced with α-Syn PFFs in the presence or absence of 24-OHC (30 μm) for 48 h. <b>(A)</b> Triton X-100 (1%) in PBS was used to permeabilize soluble proteins to observe insoluble α-Syn inclusions. Shown are the representati...

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Main Author: Lijun Dai (2407099) (author)
Other Authors: Jiannan Wang (154792) (author), Lanxia Meng (564023) (author), Xingyu Zhang (408987) (author), Tingting Xiao (838381) (author), Min Deng (114029) (author), Guiqin Chen (5955809) (author), Jing Xiong (218613) (author), Wei Ke (158476) (author), Zhengyuan Hong (20746042) (author), Lihong Bu (443666) (author), Zhentao Zhang (218622) (author)
Published: 2025
Subjects:
Biochemistry
Cell Biology
Neuroscience
Science Policy
Biological Sciences not elsewhere classified
whereas genetic removal
parkinson &# 8217
mitochondrial dysfunction induced
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nigrostriatal dopaminergic degeneration
neurodegenerative disease characterized
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cerebrospinal fluid
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