Supplementary file 1_Resveratrol attenuates pulmonary fibrosis by inhibiting alveolar epithelial senescence via targeting SASP-related proteins: an integrated bioinformatics-experimental study.docx

Supplementary file 1_Resveratrol attenuates pulmonary fibrosis by inhibiting alveolar epithelial senescence via targeting SASP-related proteins: an integrated bioinformatics-experimental study.docx

Background<p>Pulmonary fibrosis (PF) is a progressive and fatal interstitial lung disease with limited treatment options. Premature senescence of alveolar epithelial type II cells (AT2 cells) plays a critical role in PF pathogenesis. This study aimed to identify natural compounds targeting sen...

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Autore principale: Biao Zuo (1529497) (author)
Altri autori: Su Yuan (9516815) (author), Chen Luo (302288) (author), Xu-Qin Du (11434573) (author), Yong-Can Wu (22687517) (author), Li-Peng Shi (11434576) (author), Jin-Xin Chen (8430351) (author), Bo-Tao Chen (1978582) (author), Jie Zhou (28945) (author), Yi Ren (30049) (author)
Pubblicazione: 2025
Soggetti:
Pharmacology
bleomycin-induced pulmonary fibrosis in mice
resveratrol
alveolar epithelial senescence
bioinformatics
senescence-associated secretory phenotype(SASP)
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