Image_2_Decreased miR-4512 Levels in Monocytes and Macrophages of Individuals With Systemic Lupus Erythematosus Contribute to Innate Immune Activation and Neutrsophil NETosis by Targeting TLR4 and CXCL2.png

Image_2_Decreased miR-4512 Levels in Monocytes and Macrophages of Individuals With Systemic Lupus Erythematosus Contribute to Innate Immune Activation and Neutrsophil NETosis by Targeting TLR4 and CXCL2.png

Objective<p>Systemic lupus erythematosus (SLE) is an autoimmune disease with complex etiology that is not yet entirely understood. We aimed to elucidate the mechanisms and therapeutic potential of microRNAs (miRNAs) in SLE in a Tibetan population.</p>Methods<p>Peripheral blood mono...

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Bibliographic Details
Main Author: Binbin Yang (2259313) (author)
Other Authors: Xinwei Huang (286747) (author), Shuangyan Xu (3896536) (author), Li Li (14993) (author), Wei Wu (27708) (author), Yunjia Dai (10576622) (author), Ming-Xia Ge (11562511) (author), Limei Yuan (11536361) (author), Wenting Cao (11562514) (author), Meng Yang (162251) (author), Yongzhuo Wu (11562517) (author), Danqi Deng (9503502) (author)
Published: 2021
Subjects:
Immunology
Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies)
Autoimmunity
Cellular Immunology
Humoural Immunology and Immunochemistry
Immunogenetics (incl. Genetic Immunology)
Innate Immunity
Transplantation Immunology
Tumour Immunology
Immunology not elsewhere classified
Genetic Immunology
Animal Immunology
Veterinary Immunology
systemic lupus erythematosus
miR-4512
CXCl2
neutrophil extracellular trap
innate immune activation
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